Search: onr:"swepub:oai:DiVA.org:umu-50862" > Poor Folate Status ...
Fältnamn | Indikatorer | Metadata |
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000 | 03198naa a2200385 4500 | |
001 | oai:DiVA.org:umu-50862 | |
003 | SwePub | |
008 | 111229s2011 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-508622 URI |
024 | 7 | a https://doi.org/10.3945/jn.111.1442202 DOI |
040 | a (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Manger, Mari S.4 aut |
245 | 1 0 | a Poor Folate Status Predicts Persistent Diarrhea in 6-to 30-Month-Old North Indian Children |
264 | 1 | a Bethesda :b American Society for Nutrition,c 2011 |
338 | a print2 rdacarrier | |
520 | a Poor micronutrient status is associated with diarrheal illness, but it is not known whether low folate and/or cobalamin status are independent risk factors for diarrhea. We measured the association between plasma folate and cobalamin and subsequent diarrheal morbidity in a prospective cohort study of 2296 children aged 6-30 mo in New Delhi, India. Plasma concentrations of folate, cobalamin, total homocysteine (tHcy), and methylmalonic acid were determined at baseline. Whether a child had diarrhea was recorded during weekly visits in a 4-mo zinc supplementation trial. Diarrhea episodes lasting <7, >= 7, and >= 14 d were classified as acute, prolonged, and persistent, respectively. There was a total of 4596 child periods with acute, 633 with prolonged, and 117 with persistent diarrhea during follow-up. Children with plasma folate concentrations in the lowest quartile had higher odds of persistent diarrhea than children in the other quartiles [adjusted OR = 1.77(95% CI = 1.14, 2.75); P = 0.01]. This effect differed between boys [adjusted OR = 2.51 (95% CI = 1.47, 4.28)] and girls [adjusted OR = 1.03 (95% CI = 0.53, 2.01); P-interaction = 0.030]. We found a small but significant association between high plasma tHcy concentration and acute diarrhea [adjusted OR = 1.14 (95% CI = 1.04, 1.24); P = 0.006]. Plasma cobalamin concentration was not a predictor of diarrheal morbidity. In conclusion, poor folate status was an independent predictor of persistent diarrhea in this population. J. Nutr. 141: 2226-2232, 2011. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng |
700 | 1 | a Taneja, Sunita4 aut |
700 | 1 | a Strand, Tor A.4 aut |
700 | 1 | a Ueland, Per M.4 aut |
700 | 1 | a Refsum, Helga4 aut |
700 | 1 | a Schneede, Jörnu Umeå universitet,Klinisk farmakologi4 aut0 (Swepub:umu)josc0012 |
700 | 1 | a Nygard, Ottar4 aut |
700 | 1 | a Sommerfelt, Halvor4 aut |
700 | 1 | a Bhandari, Nita4 aut |
710 | 2 | a Umeå universitetb Klinisk farmakologi4 org |
773 | 0 | t Journal of Nutritiond Bethesda : American Society for Nutritiong 141:12, s. 2226-2232q 141:12<2226-2232x 0022-3166x 1541-6100 |
856 | 4 | u https://academic.oup.com/jn/article-pdf/141/12/2226/23948441/2226.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-50862 |
856 | 4 8 | u https://doi.org/10.3945/jn.111.144220 |
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