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11beta-HSD1 inhibition improves triglyceridemia through reduced liver VLDL secretion and partitions lipids toward oxidative tissues.

Berthiaume, Magalie (author)
Laplante, Mathieu (author)
Festuccia, William T (author)
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Cianflone, Katherine (author)
Turcotte, Lorraine P (author)
Joanisse, Denis R (author)
Olivecrona, Gunilla (author)
Umeå universitet,Fysiologisk kemi
Thieringer, Rolf (author)
Deshaies, Yves (author)
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 (creator_code:org_t)
2007
2007
English.
In: Am J Physiol Endocrinol Metab. - 0193-1849. ; 293:4, s. E1045-52
Related links:
http://www.ncbi.nlm....
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https://urn.kb.se/re...
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  • Journal article (peer-reviewed)
Subject headings
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Keyword

11-beta-Hydroxysteroid Dehydrogenase Type 1/*antagonists & inhibitors
Adipose Tissue; Brown/drug effects/metabolism
Animals
Enzyme Inhibitors/pharmacology
Heart/drug effects
Hypertriglyceridemia/blood/*metabolism
Lipid Metabolism/*drug effects
Lipoproteins; VLDL/*drug effects/*secretion
Liver/*drug effects/metabolism
Male
Muscle; Skeletal/drug effects/metabolism
Myocardium/metabolism
Oxidation-Reduction/drug effects
Rats
Rats; Sprague-Dawley
Triazoles/*pharmacology
Triglycerides/*secretion

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art (subject category)

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