Failure to detect Chlamydia trachomatis in cell culture by using a monoclonal antibody directed against the major outer membrane protein

Gaydos, Charlotte (author): Department of Medicine, The Johns Hopkins University, Baltimore, Maryland

Quinn, Thomas C (author): Department of Medicine, The Johns Hopkins University, Baltimore, Maryland

(creator_code:org_t)

1997
1997
English.
In: Journal of Clinical Microbiology. - 0095-1137 .- 1098-660X. ; 35:10, s. 2679-2680

Abstract Subject headings

Two commercially available monoclonal antibodies for cell culture confirmation of Chlamydia trachomatis were compared in two prospective studies and one large retrospective study. In total, more than 33,000 genital specimens were cultured in parallel and stained with both antibodies, one of which was directed against the major outer membrane protein (MOMP) and one uf which was directed against the lipopolysaccharide (LPS). We found the anti-LPS-based assay to be more sensitive and as specific as the anti-MOMP-based assay for C. trachomatis cell culture confirmation of genital specimens.

By the author/editor: Boman, Jens, 195 ...; Gaydos, Charlott ...; Juto, Per; Wadell, Göran; Quinn, Thomas C

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Clinical Laborat ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Dermatology and ...

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