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The many flavors of tumor-associated B cells

Marits, Per (author)
Karolinska Institutet
Zirakzadeh, Ali A (author)
Karolinska Institutet
Sherif, Amir (author)
Umeå universitet,Urologi och andrologi
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Winqvist, Ola (author)
Karolinska Institutet
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 (creator_code:org_t)
2014-10-27
2013
English.
In: Oncoimmunology. - : Landes Bioscience. - 2162-4011 .- 2162-402X. ; 2:8, s. e25237-
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Little is known on the role of distinct B-cell subtypes in human malignancies. We have recently performed a multiplex characterization of B cells in patient-derived tumor-associated tissues, documenting the activation and antigen-driven differentiation of B cells in metastatic lymph nodes and neoplastic lesions. Here we discuss the role of B lymphocytes as antigen-presenting cells and catalysts of T cell-based immunotherapies in view of these findings.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Immunologi inom det medicinska området (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Immunology in the medical area (hsv//eng)

Keyword

adoptive immunotherapy
antigen-presenting cell
B-cell subtypes
clonal expansion
tumor-draining lymph nodes

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ref (subject category)
art (subject category)

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Marits, Per
Zirakzadeh, Ali ...
Sherif, Amir
Winqvist, Ola
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MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
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and Cancer and Oncol ...
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Basic Medicine
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Oncoimmunology
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Umeå University
Karolinska Institutet

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