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Long-term effects o...
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Mellberg, CarolineUmeå universitet,Medicin
(author)
Long-term effects of a Palaeolithic-type diet in obese postmenopausal women : a 2-year randomized trial
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Publisher, publication year, extent ...
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2014-01-29
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Nature Publishing Group,2014
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:umu-86275
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-86275URI
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https://doi.org/10.1038/ejcn.2013.290DOI
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https://gup.ub.gu.se/publication/190365URI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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C. Mellberg, S. Sandberg and M. Ryberg share first authorship.T. Olsson and B. Lindahl share senior authorship.
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Background/Objectives: Short-term studies have suggested beneficial effects of a Palaeolithic-type diet (PD) on body weight and metabolic balance. We now report the long-term effects of a PD on anthropometric measurements and metabolic balance in obese postmenopausal women, in comparison with a diet according to the Nordic Nutrition Recommendations (NNR).Subjects/Methods: Seventy obese postmenopausal women (mean age 60 years, body mass index 33 kg/m(2)) were assigned to an ad libitum PD or NNR diet in a 2-year randomized controlled trial. The primary outcome was change in fat mass as measured by dual-energy X-ray absorptiometry.Results: Both groups significantly decreased total fat mass at 6 months (-6.5 and-2.6 kg) and 24 months (-4.6 and-2.9 kg), with a more pronounced fat loss in the PD group at 6 months (P<0.001) but not at 24 months (P=0.095). Waist circumference and sagittal diameter also decreased in both the groups, with a more pronounced decrease in the PD group at 6 months (-11.1 vs-5.8 cm, P=0.001 and-3.7 vs-2.0 cm, P<0.001, respectively). Triglyceride levels decreased significantly more at 6 and 24 months in the PD group than in the NNR group (P<0.001 and P=0.004). Nitrogen excretion did not differ between the groups.Conclusions: A PD has greater beneficial effects vs an NNR diet regarding fat mass, abdominal obesity and triglyceride levels in obese postmenopausal women; effects not sustained for anthropometric measurements at 24 months. Adherence to protein intake was poor in the PD group. The long-term consequences of these changes remain to be studied.
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Sandberg, SusanneUmeå universitet,Yrkes- och miljömedicin(Swepub:umu)suesag76
(author)
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Ryberg, MatsUmeå universitet,Medicin(Swepub:umu)mary0013
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Eriksson, MarieUmeå universitet,Statistik(Swepub:umu)maer0004
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Brage, SMRC Epidemiology Unit, University of Cambridge, Cambridge, UK
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Larsson, ChristelGothenburg University,Göteborgs universitet,Umeå universitet,Institutionen för kostvetenskap,Department of Food and Nutrition, and Sport Science, University of Gothenburg, Gothenburg,Institutionen för kost- och idrottsvetenskap,Department of Food and Nutrition, and Sport Science(Swepub:gu)xlachr
(author)
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Olsson, TommyUmeå universitet,Medicin(Swepub:umu)tool0003
(author)
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Lindahl, BerntUmeå universitet,Yrkes- och miljömedicin(Swepub:umu)beli0020
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Umeå universitetMedicin
(creator_code:org_t)
Related titles
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In:European Journal of Clinical Nutrition: Nature Publishing Group68:3, s. 350-70954-30071476-5640
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