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  • Cohen, Cheryl (author)

Severe Influenza-associated Respiratory Infection in High HIV Prevalence Setting, South Africa, 2009-2011

  • Article/chapterEnglish2013

Publisher, publication year, extent ...

  • Centers for Disease Control and Prevention (CDC),2013
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:umu-86857
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-86857URI
  • https://doi.org/10.3201/eid1911.130546DOI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Data on influenza epidemiology in HIV-infected persons are limited, particularly for sub-Saharan Africa, where HIV infection is widespread. We tested respiratory and blood samples from patients with acute lower respiratory tract infections hospitalized in South Africa during 2009-2011 for viral and pneumococcal infections. Influenza was identified in 9% (1,056/11,925) of patients enrolled; among influenza case-patients, 358 (44%) of the 819 who were tested were infected with HIV. Influenza-associated acute lower respiratory tract infection incidence was 4-8 times greater for HIV-infected (186-228/100,000) than for HIV-uninfected persons (26-54/100,000). Furthermore, multivariable analysis showed HIV-infected patients were more likely to have pneumococcal co-infection; to be infected with influenza type B compared with type A; to be hospitalized for 2-7 days or >7 days; and to die from their illness. These findings indicate that HIV-infected persons are at greater risk for severe illnesses related to influenza and thus should be prioritized for influenza vaccination.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Moyes, Jocelyn (author)
  • Tempia, Stefano (author)
  • Groom, Michelle (author)
  • Walaza, Sibongile (author)
  • Pretorius, Marthi (author)
  • Dawood, Halima (author)
  • Chhagan, Meera (author)
  • Haffejee, Summaya (author)
  • Variava, Ebrahim (author)
  • Kahn, KathleenUmeå universitet,Epidemiologi och global hälsa(Swepub:umu)kaka0045 (author)
  • Tshangela, Akhona (author)
  • von Gottberg, Anne (author)
  • Wolter, Nicole (author)
  • Cohen, Adam L. (author)
  • Kgokong, Babatyi (author)
  • Venter, Marietjie (author)
  • Madhi, Shabir A. (author)
  • Umeå universitetEpidemiologi och global hälsa (creator_code:org_t)

Related titles

  • In:Emerging Infectious Diseases: Centers for Disease Control and Prevention (CDC)19:11, s. 1766-17741080-60401080-6059

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