Search: onr:"swepub:oai:DiVA.org:umu-90429" >
Tumour characterist...
Tumour characteristics and surgical treatment of renal cell carcinoma in Sweden 2005-2010 : a population-based study from the National Swedish Kidney Cancer Register
-
Thorstenson, Andreas (author)
-
Bergman, Martin, 1985 (author)
-
Scherman-Plogell, Ann-Helen (author)
-
show more...
-
Hosseinnia, Soheila (author)
-
- Ljungberg, Börje (author)
- Umeå universitet,Urologi och andrologi,Njurcancer
-
- Adolfsson, Jan (author)
- Karolinska Institutet
-
Lundstam, Sven (author)
-
show less...
-
(creator_code:org_t)
- 2014-03-25
- 2014
- English.
-
In: Scandinavian journal of urology. - Abingdon : Taylor & Francis. - 2168-1805 .- 2168-1813. ; 48:3, s. 231-238
- Related links:
-
http://dx.doi.org/10...
-
show more...
-
https://urn.kb.se/re...
-
https://doi.org/10.3...
-
https://research.cha...
-
http://kipublication...
-
show less...
Abstract
Subject headings
Close
- Objective. Tumour characteristics, preoperative work-up and surgical treatment in patients diagnosed with renal cell carcinoma (RCC) between 2005 and 2010, and changes over time were studied in a national population-based cohort. Material and methods. The National Swedish Kidney Cancer Register (NSKCR) contains information on histopathology, Fuhrman grade and clinical stage at presentation, and on the preoperative work-up and surgical treatment of patients with RCC. Between 2005 and 2010, 5553 RCC patients were registered in the NSKCR, 99% of those registered in the National Cancer Registry. Results. During the study period the mean tumour size decreased from 70 to 64 mm (p = 0.024) and the frequency of metastatic RCC decreased from 22% to 15% (p < 0.001). The use of preoperative chest computed tomography increased from 59% to 84%. In total, 4229 (76%) patients were treated with curative intent, 3453 (82%) underwent radical nephrectomy, 606 (14%) partial nephrectomy (PN) and 170 (4%) cryotherapy or radiofrequency ablation. In tumours up to 4 cm, PN was performed in 33% of the surgically treated patients. PN irrespective of size increased from 8% to 20% and laparoscopic nephrectomy increased from 6% to 17% during the period. In patients with metastatic RCC, 55% underwent cytoreductive nephrectomy. Conclusions. The NSKCR explores population-based data on the clinical handling of patients with RCC. This study, between 2005 and 2010, shows significant decrease in tumour size and metastatic RCC at presentation, a more complete preoperative work-up, and significantly increased use of PN and laparoscopic nephrectomy in Sweden.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- distant metastasis
- lymph-node metastasis
- population-based
- renal cell carcinoma
- survival
- tumour category
- tumour size
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database