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Vitamin D and multi...
Vitamin D and multiple sclerosis : where do we go from here?
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- Salzer, Jonatan (author)
- Umeå universitet,Klinisk neurovetenskap
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- Biström, Martin (author)
- Umeå universitet,Klinisk neurovetenskap
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- Sundström, Peter (author)
- Umeå universitet,Klinisk neurovetenskap
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(creator_code:org_t)
- 2013-12-09
- 2014
- English.
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In: Expert Review of Neurotherapeutics. - : Informa. - 1473-7175 .- 1744-8360. ; 14:1, s. 9-18
- Related links:
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https://urn.kb.se/re...
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Abstract
Subject headings
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- This article briefly introduces the basics of multiple sclerosis' (MS) clinical hallmarks and pathophysiology. Vitamin D is presented, including its metabolism and effects on the immune system. The epidemiological observations linking vitamin D to MS range from a half century old findings of latitude gradients and migrational risk patterns to modern, nested, case-control biobank studies. These observations show an association without doubt although causation has yet to be proven. Vitamin D as a treatment for MS is an emerging concept and both current and anticipated data will be covered. Lastly, we discuss future challenges, ideas on how to move from association to causation, and the prospect of primary prevention of this disabling disease.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Keyword
- multiple sclerosis
- primary prevention
- prospective biobank studies
- randomized controlled trials
- ultraviolet B (UVB) radiation
- vitamin D
Publication and Content Type
- ref (subject category)
- for (subject category)
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