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Cross-sectional ass...
Cross-sectional associations between air pollution and chronic bronchitis : an ESCAPE meta-analysis across five cohorts
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Cai, Yutong (author)
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Schikowski, Tamara (author)
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Adam, Martin (author)
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Buschka, Anna (author)
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Carsin, Anne-Elie (author)
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Jacquemin, Benedicte (author)
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Marcon, Alessandro (author)
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Sanchez, Margaux (author)
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Vierkötter, Andrea (author)
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Al-Kanaani, Zaina (author)
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Beelen, Rob (author)
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Birk, Matthias (author)
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Brunekreef, Bert (author)
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Cirach, Marta (author)
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Clavel-Chapelon, Françoise (author)
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Declercq, Christophe (author)
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de Hoogh, Kees (author)
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de Nazelle, Audrey (author)
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Ducret-Stich, Regina E. (author)
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Valeria Ferretti, Virginia (author)
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- Forsberg, Bertil (author)
- Umeå universitet,Yrkes- och miljömedicin,Arcum
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Gerbase, Margaret W. (author)
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Hardy, Rebecca (author)
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Heinrich, Joachim (author)
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Hoek, Gerard (author)
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Jarvis, Debbie (author)
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Keidel, Dirk (author)
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Kuh, Diana (author)
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Nieuwenhuijsen, Mark J. (author)
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Ragettli, Martina S. (author)
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Ranzi, Andrea (author)
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Rochat, Thierry (author)
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Schindler, Christian (author)
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Sugiri, Dorothea (author)
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Temam, Sofia (author)
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Tsai, Ming-Yi (author)
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Varraso, Raphaëlle (author)
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Kauffmann, Francine (author)
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Krämer, Ursula (author)
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Sunyer, Jordi (author)
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Künzli, Nino (author)
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Probst-Hensch, Nicole (author)
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Hansell, Anna L. (author)
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(creator_code:org_t)
- 2014-08-11
- 2014
- English.
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In: Thorax. - : BMJ. - 0040-6376 .- 1468-3296. ; 69:11, s. 1005-1014
- Related links:
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https://thorax.bmj.c...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- BACKGROUND: This study aimed to assess associations of outdoor air pollution on prevalence of chronic bronchitis symptoms in adults in five cohort studies (Asthma-E3N, ECRHS, NSHD, SALIA, SAPALDIA) participating in the European Study of Cohorts for Air Pollution Effects (ESCAPE) project.METHODS: Annual average particulate matter (PM10, PM2.5, PMabsorbance, PMcoarse), NO2, nitrogen oxides (NOx) and road traffic measures modelled from ESCAPE measurement campaigns 2008-2011 were assigned to home address at most recent assessments (1998-2011). Symptoms examined were chronic bronchitis (cough and phlegm for ≥3 months of the year for ≥2 years), chronic cough (with/without phlegm) and chronic phlegm (with/without cough). Cohort-specific cross-sectional multivariable logistic regression analyses were conducted using common confounder sets (age, sex, smoking, interview season, education), followed by meta-analysis.RESULTS: 15 279 and 10 537 participants respectively were included in the main NO2 and PM analyses at assessments in 1998-2011. Overall, there were no statistically significant associations with any air pollutant or traffic exposure. Sensitivity analyses including in asthmatics only, females only or using back-extrapolated NO2 and PM10 for assessments in 1985-2002 (ECRHS, NSHD, SALIA, SAPALDIA) did not alter conclusions. In never-smokers, all associations were positive, but reached statistical significance only for chronic phlegm with PMcoarse OR 1.31 (1.05 to 1.64) per 5 µg/m(3) increase and PM10 with similar effect size. Sensitivity analyses of older cohorts showed increased risk of chronic cough with PM2.5abs (black carbon) exposures.CONCLUSIONS: Results do not show consistent associations between chronic bronchitis symptoms and current traffic-related air pollution in adult European populations.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
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- art (subject category)
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Cai, Yutong
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Schikowski, Tama ...
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Adam, Martin
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Buschka, Anna
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Carsin, Anne-Eli ...
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Jacquemin, Bened ...
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show more...
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Marcon, Alessand ...
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Sanchez, Margaux
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Vierkötter, Andr ...
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Al-Kanaani, Zain ...
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Beelen, Rob
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Birk, Matthias
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Brunekreef, Bert
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Cirach, Marta
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Clavel-Chapelon, ...
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Declercq, Christ ...
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de Hoogh, Kees
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de Nazelle, Audr ...
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Ducret-Stich, Re ...
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Valeria Ferretti ...
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Forsberg, Bertil
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Gerbase, Margare ...
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Hardy, Rebecca
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Heinrich, Joachi ...
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Hoek, Gerard
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Jarvis, Debbie
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Keidel, Dirk
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Kuh, Diana
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Nieuwenhuijsen, ...
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Ragettli, Martin ...
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Ranzi, Andrea
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Rochat, Thierry
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Schindler, Chris ...
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Sugiri, Dorothea
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Temam, Sofia
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Tsai, Ming-Yi
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Varraso, Raphaël ...
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Kauffmann, Franc ...
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Krämer, Ursula
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Sunyer, Jordi
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Künzli, Nino
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Probst-Hensch, N ...
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Hansell, Anna L.
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Occupational Hea ...
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Thorax
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Umeå University