Search: onr:"swepub:oai:DiVA.org:umu-96595" > Weight change in mi...
Fältnamn | Indikatorer | Metadata |
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000 | 05708naa a2201009 4500 | |
001 | oai:DiVA.org:umu-96595 | |
003 | SwePub | |
008 | 141124s2014 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:98732c14-f299-4176-b60a-dd8eea283353 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-965952 URI |
024 | 7 | a https://doi.org/10.1002/ijc.289262 DOI |
024 | 7 | a https://lup.lub.lu.se/record/47839412 URI |
040 | a (SwePub)umud (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Emaus, Marleen J.4 aut |
245 | 1 0 | a Weight change in middle adulthood and breast cancer risk in the EPIC-PANACEA study |
264 | c 2014-05-16 | |
264 | 1 | b Wiley,c 2014 |
338 | a print2 rdacarrier | |
520 | a Long-term weight gain (i.e., weight gain since age 20) has been related to higher risk of postmenopausal breast cancer, but a lower risk of premenopausal breast cancer. The effect of weight change in middle adulthood is unclear. We investigated the association between weight change in middle adulthood (i.e., women aged 40-50 years) and the risk of breast cancer before and after the age of 50. We included female participants of the European Prospective Investigation into Cancer and Nutrition cohort, with information on anthropometric measures at recruitment and after a median follow-up of 4.3 years. Annual weight change was categorized using quintiles taking quintile 2 and 3 as the reference category (-0.44 to 0.36 kg/year). Multivariable Cox proportional hazards regression analysis was used to examine the association. 205,723 women were included and 4,663 incident breast cancer cases were diagnosed during a median follow-up of 7.5 years (from second weight assessment onward). High weight gain (Q5: 0.83-4.98 kg/year) was related to a slightly, but significantly higher breast cancer risk (HRQ5_versus_Q2/3: 1.09, 95% CI: 1.01-1.18). The association was more pronounced for breast cancer diagnosed before or at age 50 (HRQ5_versus_Q2/3: 1.37, 95% CI: 1.02-1.85). Weight loss was not associated with breast cancer risk. There was no evidence for heterogeneity by hormone receptor status. In conclusion, high weight gain in middle adulthood increases the risk of breast cancer. The association seems to be more pronounced for breast cancer diagnosed before or at age 50. Our results illustrate the importance of avoiding weight gain in middle adulthood. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
653 | a breast cancer | |
653 | a adult weight gain | |
653 | a menopausal status | |
653 | a estrogen receptor | |
653 | a progesterone receptor | |
653 | a breast cancer | |
653 | a adult weight gain | |
653 | a menopausal status | |
653 | a estrogen receptor | |
653 | a progesterone receptor | |
700 | 1 | a van Gils, Carla H.4 aut |
700 | 1 | a Bakker, Marije F.4 aut |
700 | 1 | a Bisschop, Charlotte N. Steins4 aut |
700 | 1 | a Monninkhof, Evelyn M.4 aut |
700 | 1 | a Bueno-de-Mesquita, H. B(as)4 aut |
700 | 1 | a Travier, Noemie4 aut |
700 | 1 | a Berentzen, Tina Landsvig4 aut |
700 | 1 | a Overvad, Kim4 aut |
700 | 1 | a Tjonneland, Anne4 aut |
700 | 1 | a Romieu, Isabelle4 aut |
700 | 1 | a Rinaldi, Sabina4 aut |
700 | 1 | a Chajes, Veronique4 aut |
700 | 1 | a Gunter, Marc J.4 aut |
700 | 1 | a Clavel-Chapelon, Francoise4 aut |
700 | 1 | a Fagherazzi, Guy4 aut |
700 | 1 | a Mesrine, Sylvie4 aut |
700 | 1 | a Chang-Claude, Jenny4 aut |
700 | 1 | a Kaaks, Rudolf4 aut |
700 | 1 | a Boeing, Heiner4 aut |
700 | 1 | a Aleksandrova, Krasimira4 aut |
700 | 1 | a Trichopoulou, Antonia4 aut |
700 | 1 | a Naska, Androniki4 aut |
700 | 1 | a Orfanos, Philippos4 aut |
700 | 1 | a Palli, Domenico4 aut |
700 | 1 | a Agnoli, Claudia4 aut |
700 | 1 | a Tumino, Rosario4 aut |
700 | 1 | a Vineis, Paolo4 aut |
700 | 1 | a Mattiello, Amalia4 aut |
700 | 1 | a Braaten, Tonje4 aut |
700 | 1 | a Borch, Kristin Benjaminsen4 aut |
700 | 1 | a Lund, Eiliv4 aut |
700 | 1 | a Menendez, Virginia4 aut |
700 | 1 | a Sanchez, Maria-Jose4 aut |
700 | 1 | a Navarro, Carmen4 aut |
700 | 1 | a Barricarte, Aurelio4 aut |
700 | 1 | a Amiano, Pilar4 aut |
700 | 1 | a Sund, Malin,d 1972-u Umeå universitet,Kirurgi4 aut0 (Swepub:umu)masu0021 |
700 | 1 | a Andersson, Anneu Umeå universitet,Onkologi4 aut0 (Swepub:umu)ankr0012 |
700 | 1 | a Borgquist, Signeu Lund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)ront-sbo |
700 | 1 | a Olsson, Åsau Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)med-aol |
700 | 1 | a Khaw, Kay-Tee4 aut |
700 | 1 | a Wareham, Nick4 aut |
700 | 1 | a Travis, Ruth C.4 aut |
700 | 1 | a Riboli, Elio4 aut |
700 | 1 | a Peeters, Petra H. M.4 aut |
700 | 1 | a May, Anne M.4 aut |
710 | 2 | a Umeå universitetb Kirurgi4 org |
773 | 0 | t International Journal of Cancerd : Wileyg 135:12, s. 2887-2899q 135:12<2887-2899x 0020-7136x 1097-0215 |
856 | 4 | u http://dx.doi.org/10.1002/ijc.28926y FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-96595 |
856 | 4 8 | u https://doi.org/10.1002/ijc.28926 |
856 | 4 8 | u https://lup.lub.lu.se/record/4783941 |
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