SwePub
Sök i LIBRIS databas

  Extended search

onr:"swepub:oai:DiVA.org:umu-99353"
 

Search: onr:"swepub:oai:DiVA.org:umu-99353" > GRIM REAPER peptide...

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

GRIM REAPER peptide binds to receptor kinase PRK5 to trigger cell death in Arabidopsis

Wrzaczek, Michael (author)
Vainonen, Julia P. (author)
Stael, Simon (author)
show more...
Tsiatsiani, Liana (author)
Help-Rinta-Rahko, Hanna (author)
Gauthier, Adrien (author)
Kaufholdt, David (author)
Bollhöner, Benjamin (author)
Umeå universitet,Institutionen för fysiologisk botanik,Umeå Plant Science Centre (UPSC)
Lamminmaki, Airi (author)
Staes, An (author)
Gevaert, Kris (author)
Tuominen, Hannele (author)
Umeå universitet,Institutionen för fysiologisk botanik,Umeå Plant Science Centre (UPSC)
Van Breusegem, Frank (author)
Helariutta, Yka (author)
Kangasjarvi, Jaakko (author)
show less...
 (creator_code:org_t)
2014-11-14
2015
English.
In: EMBO Journal. - : EMBO. - 0261-4189 .- 1460-2075. ; 31:1, s. 55-66
Related links:
https://onlinelibrar...
show more...
https://urn.kb.se/re...
https://doi.org/10.1...
show less...
  • Journal article (peer-reviewed)
Abstract Subject headings
Close  
  • Recognition of extracellular peptides by plasma membrane-localized receptor proteins is commonly used in signal transduction. In plants, very little is known about how extracellular peptides are processed and activated in order to allow recognition by receptors. Here, we show that induction of cell death in planta by a secreted plant protein GRIM REAPER (GRI) is dependent on the activity of the type II metacaspase METACASPASE-9. GRI is cleaved by METACASPASE-9 in vitro resulting in the release of an 11 amino acid peptide. This peptide bound in vivo to the extracellular domain of the plasma membrane-localized, atypical leucine-rich repeat receptor-like kinase POLLEN-SPECIFIC RECEPTOR-LIKE KINASE 5 (PRK5) and was sufficient to induce oxidative stress/ROS-dependent cell death. This shows a signaling pathway in plants from processing and activation of an extracellular protein to recognition by its receptor.

Subject headings

NATURVETENSKAP  -- Biologi -- Genetik (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences -- Genetics (hsv//eng)
NATURVETENSKAP  -- Biologi -- Botanik (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences -- Botany (hsv//eng)

Keyword

ligand
protease
receptor-like kinase
secreted protein

Publication and Content Type

ref (subject category)
art (subject category)

Find in a library

To the university's database

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view