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QUEST-RA :
QUEST-RA : quantitative clinical assessment of patients with rheumatoid arthritis seen in standard rheumatology care in 15 countries
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Sokka, Tuulikki (author)
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Kautiainen, Hannu (author)
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Toloza, Sergio (author)
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Mäkinen, Heidi (author)
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Verstappen, Suzan M. (author)
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Lund Hetland, Merete (author)
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Naranjo, Antonio (author)
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- Baecklund, Eva (author)
- Uppsala universitet,Reumatologi
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Herborn, Gertraud (author)
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Rau, Rolf (author)
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Cazzato, Massimiliano (author)
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Gossec, Laure (author)
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Skakic, Vlado (author)
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Gogus, Feride (author)
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Sierakowski, Stanislaw (author)
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Bresnihan, Barry (author)
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Taylor, Peter (author)
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McClinton, Catherine (author)
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Pincus, Theodore (author)
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(creator_code:org_t)
- BMJ, 2007
- 2007
- English.
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In: Annals of the Rheumatic Diseases. - : BMJ. - 0003-4967 .- 1468-2060. ; 66:11, s. 1491-1496
- Related links:
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https://europepmc.or...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- OBJECTIVE:To conduct a cross-sectional review of non-selected consecutive outpatients with rheumatoid arthritis (RA) as part of standard clinical care in 15 countries for an overview of the characteristics of patients with RA.METHODS:The review included current disease activity using data from clinical assessment and a patient self-report questionnaire, which was translated into each language. Data on demographic, disease and treatment-related variables were collected and analysed using descriptive statistics. Variation in disease activity on DAS28 (disease activity score on 28-joint count) within and between countries was graphically analysed. A median regression model was applied to analyse differences in disease activity between countries.RESULTS:Between January 2005 and October 2006, the QUEST-RA (Quantitative Patient Questionnaires in Standard Monitoring of Patients with Rheumatoid Arthritis) project included 4363 patients from 48 sites in 15 countries; 78% were female, >90% Caucasian, mean age was 57 years and mean disease duration was 11.5 years. More than 80% of patients had been treated with methotrexate in all but three countries. Overall, patients had an active disease with a median DAS28 of 4.0, with a significant variation between countries (p<0.001). Among 42 sites with >50 patients included, low disease activity of DAS28 50% of patients had high disease activity of DAS28 >5.1.CONCLUSIONS:This international multicentre cross-sectional database provides an overview of clinical status and treatments of patients with RA in standard clinical care in 2005-6 including countries that are infrequently involved in clinical research projects.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Keyword
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Sokka, Tuulikki
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Kautiainen, Hann ...
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Toloza, Sergio
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Mäkinen, Heidi
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Verstappen, Suza ...
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Lund Hetland, Me ...
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show more...
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Naranjo, Antonio
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Baecklund, Eva
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Herborn, Gertrau ...
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Rau, Rolf
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Cazzato, Massimi ...
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Gossec, Laure
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Skakic, Vlado
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Gogus, Feride
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Sierakowski, Sta ...
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Bresnihan, Barry
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Taylor, Peter
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McClinton, Cathe ...
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Pincus, Theodore
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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Annals of the Rh ...
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Uppsala University