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Multiple medicine u...
Multiple medicine use: factors of importance in different age groups
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- Moen, Janne, 1980- (author)
- Uppsala universitet,Institutionen för farmaci,Pharmaceutical Outcomes Research Group
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- Antonov, Karolina (author)
- The Swedish Association of the Pharmaceutical Industry,Pharmaceutical Outcomes Research Group
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- Larsson, Charlotte A. (author)
- Department of Clinical Sciences, Lund University
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- Lindblad, Ulf (author)
- Department of Public Health and Community Medicine/Primary Health Care, The Sahlgrenska Academy at Gothenburg University and The Skaraborg Institute
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- Nilsson, J. Lars G. (author)
- The NEPI Foundation
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- Råstam, Lennart (author)
- Department of Clinical Sciences, Lund University
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- Ring, Lena (author)
- Uppsala universitet,Institutionen för farmaci,Pharmaceutical Outcomes Research Group
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(creator_code:org_t)
- English.
- Related links:
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https://urn.kb.se/re...
Abstract
Subject headings
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- BACKGROUND: Multiple medicine use among elderly persons is likely to be the result of treatment regimens developed over a long time. By learning more about this development, it might be possible to increase quality in management of multiple medicine use across the adult lifespan. OBJECTIVE: To describe patterns of multiple medicine use in a general population in association with sociodemographic factors, lifestyle, and health status. METHODS: Data from a cross-sectional population health survey collected during 2001-2005 in 2,816 randomly selected Swedish residents (age 30-75 years; response rate 76%). Multiple medicine use was defined as the upper quartile in each age cohort. RESULTS: The cut-offs defining multiple medicine use were: ≥2 for 30-49 year olds, ≥3 for 50-64 year olds, and ≥5 for 65-75 year olds. When drugs were classified into the second level of the ATC code, 76.3% of the 30-49 year olds, 97.9% of the 50-64 year olds, and 100% of the 65-75 year olds used a unique combination of drugs. The multivariate analyses showed that diabetes and poor self-rated health were associated with multiple medicine use in all age cohorts. Female gender and hypertension were associated with multiple medicine use among 30-49 and 50-64 year olds, ex-smoking among 50-64 year olds, and obesity among 65-75 year olds. CONCLUSIONS: Different cut-offs should be used in defining multiple medicine use in different age groups. A vast majority of users of multiple medicines have a unique drug combination. Multiple medicine use is associated with morbidity and poor self-rated health across all age groups, suggesting that multiple medicine use is not due to drug over-consumption.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Samhällsfarmaci och klinisk farmaci (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Social and Clinical Pharmacy (hsv//eng)
Keyword
- health status factors
- lifestyle factors
- multiple medicine use
- polypharmacy
- population survey
- self-rated health
- sociodemographic factors
- Community pharmacy services
- Samhällsfarmaci
Publication and Content Type
- vet (subject category)
- ovr (subject category)
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