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Menstrual cycle len...
Menstrual cycle length is an age-independent marker of female fertility : results from 6271 treatment cycles of in vitro fertilization
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- Brodin, Thomas (author)
- Uppsala universitet,Institutionen för kvinnors och barns hälsa,Klinisk och experimentell reproduktionsbiologi/Olovsson
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Bergh, Torbjorn (author)
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Berglund, Lars (author)
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Hadziosmanovic, Nermin (author)
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- Holte, Jan (author)
- Uppsala universitet,Institutionen för kvinnors och barns hälsa,Klinisk och experimentell reproduktionsbiologi/Olovsson
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(creator_code:org_t)
- Elsevier BV, 2008
- 2008
- English.
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In: Fertility and Sterility. - : Elsevier BV. - 0015-0282 .- 1556-5653. ; 90:5, s. 1656-1661
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- OBJECTIVE: To investigate whether menstrual cycle length correlates with success rates at IVF/intracytoplasmic sperm injection (ICSI) and could be used as a marker of ovarian reserve. DESIGN: Prospective observational study. SETTING: Private infertility centre. PATIENT(S): A total of 6271 IVF/ICSI treatment cycles. INTERVENTION(S): Self-reported mean number of menstrual days during the last year was recorded before initiation of IVF/ICSI treatment. MAIN OUTCOME MEASURE(S): Relations between menstrual cycle length and pregnancy and delivery rates. RESULT(S): Increasing age was associated with a subtle shortening of mean menstrual cycle length. Menstrual cycle length correlated linearly with pregnancy and delivery rates, even after age adjustment. The chance of delivery after IVF/ICSI was almost doubled for women with a menstrual cycle length >34 days compared with women with a menstrual cycle length <26 days. Menstrual cycle length was also significantly associated with ovarian response to FSH/hMG stimulation and embryo quality. CONCLUSION(S): Mean menstrual cycle length is highly related to success rates in assisted reproduction, independently of age. A precise menstrual cycle history could be used as a simple marker of ovarian reserve.
Keyword
- Fecundity
- female age
- infertility
- IVF
- menstrual cycle
- ovarian reserve
Publication and Content Type
- ref (subject category)
- art (subject category)
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