Kolonspiroketos - behandlingsbart och värt att uppmärksamma: Erfarenheter från pediatrisk praktik

Kolonspiroketos - behandlingsbart och värt att uppmärksamma : Erfarenheter från pediatrisk praktik

This article is written to raise awareness among clinicians and pathologists regarding the existence of colonic spirochetosis. Whether this is of clinical significance is still a matter of debate. We report a series of sixteen randomly selected patients, all of paediatric age; eight of them have been reported in a previous publication (10). In one patient, spirochetes were found both in the colon and in the liver. The colon organisms were Brachyspira aalborgi, documented by antigen test; however, due to lack of material, the spirochetes in the liver could not be typed. As 10 of 13 patients recovered or improved after antibiotic treatment with clarythromycin or metronidazole, our conclusion is that Brachyspira may be pathogenic. We suggest that when a rectosigmoidoscopy/colonoscopy is performed, colonic spirochetosis should be considered, especially in the differential diagnosis to microscopic colitis.

Saksena, Pushpa (author)
Saalman, Robert (author)
Korlén, Bengt (author)
Lucas, Steven (author)
Sabzwari, Nusrat (author)
Carlén, Birgitta (author)
Engstrand, Lars (author)
Wanders, AlkwinUppsala universitet,Institutionen för genetik och patologi(Swepub:uu)alkwwand (author)
Willén, RogerUppsala universitet,Institutionen för genetik och patologi (author)
Uppsala universitetInstitutionen för genetik och patologi (creator_code:org_t)

By the author/editor: Marthinsen, Lars; Saksena, Pushpa; Saalman, Robert; Korlén, Bengt; Lucas, Steven; Sabzwari, Nusrat; show more...; Carlén, Birgitta; Engstrand, Lars; Wanders, Alkwin; Willén, Roger; show less...

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