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- Devenney, IreneLinköpings universitet,Pediatrik,Hälsouniversitetet (author)
A new model for low-dose food challenge in children with allergy to milk or egg.
- Article/chapterEnglish2006
Publisher, publication year, extent ...
- Wiley,2006
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:uu-11968
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-11968URI
- https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-14561URI
- https://doi.org/10.1080/08035250500516672DOI
Supplementary language notes
- Language:English
- Summary in:English
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- SwePubSwePub
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Notes
- Division of Paediatrics, Department of Molecular and Clinical Medicine, Faculty of Health Sciences, Linköping University, Linköping, and Paediatric Clinic, County Hospital Ryhov, Fonköping, Sweden. irene.devenney@lio.seBACKGROUND: Atopic eczema and food allergy are common in early childhood. Children seem to gradually develop tolerance to milk and egg, and it is a relief for families when their child can tolerate small amounts of these basic foods, even if larger doses may still cause symptoms. AIM: To develop a model for low-dose oral food challenge, facilitating re-/introduction of milk or egg. METHODS: In 39 children sensitized to milk and/or egg, we performed 52 challenges using a new standardized model for low-dose oral food challenge. The recipes were validated for blinding with sensorial tests. RESULTS: Four children challenged to milk had a positive challenge outcome. There were no significant differences with respect to family history, associated atopic manifestations, nutritional supply, eczema severity, or skin-prick test compared with the non-reacting children, but total and specific IgE values were significantly higher. All but two of the non-reacting children were able to introduce milk and egg into their diet without problems. CONCLUSION: We report recipes and a protocol to be used for standardized open and double-blind placebo-controlled low-dose food challenge in young children, enabling the introduction of small amounts of egg and milk into the diet during tolerance development.
Subject headings and genre
- Child; Preschool
- Cookery/*methods
- Double-Blind Method
- Egg Hypersensitivity/*therapy
- Female
- Humans
- Infant
- Male
- Milk Hypersensitivity/*therapy
- Prospective Studies
- Taste
- Treatment Outcome
- MEDICINE
Added entries (persons, corporate bodies, meetings, titles ...)
- Norrman, GunillaLinköpings universitet,Uppsala universitet,Centrum för klinisk forskning, Gävleborg,Pediatrik,Hälsouniversitetet(Swepub:liu)gunjo87 (author)
- Oldaeus, GöranPaediatric Clinic, County Hospital Ryhov, Jönköping, Sweden(Swepub:liu)gorol11 (author)
- Strömberg, LeifPaediatric Clinic, Vrinnevi Hospital, Norrköping, Sweden (author)
- Fälth-Magnusson, KarinLinköpings universitet,Pediatrik,Hälsouniversitetet(Swepub:liu)karfa12 (author)
- Linköpings universitetPediatrik (creator_code:org_t)
Related titles
- In:Acta Paediatr: Wiley95:9, s. 1133-90803-52531651-2227
Internet link
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=16938763&dopt=Citation
- http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-7128Link to Ph.D. thesis (Devenney)
- http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-9048Link to Ph.D. thesis (Norrman)
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-11968
- https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-14561
- https://doi.org/10.1080/08035250500516672
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