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Heart rate variabil...
Heart rate variability (HRV) in adolescent females with anxiety disorders and major depressive disorder
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- Henje Blom, Eva, 1962- (author)
- Karolinska Institutet
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- Olsson, Erik (author)
- Uppsala universitet,Institutionen för psykologi,Department of Psychology, Uppsala University, Uppsala, Swede
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- Serlachius, E. (author)
- Karolinska Institutet
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- Ericson, Mats (author)
- Försvarshögskolan
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- Ingvar, M. (author)
- Karolinska Institutet
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(creator_code:org_t)
- Wiley, 2010
- 2010
- English.
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In: Acta Paediatrica. - : Wiley. - 0803-5253 .- 1651-2227. ; 99:4, s. 604-611
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Abstract
Subject headings
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- AIM: The aim of this study was to investigate heart rate variability (HRV) in a clinical sample of female adolescents with anxiety disorders (AD) and/or major depressive disorder (MDD) compared with healthy controls and to assess the effect of selective serotonin reuptake inhibitors (SSRI) on HRV. METHODS: Heart rate variability was measured in adolescent female psychiatric patients with AD and/or MDD (n = 69), mean age 16.8 years (range: 14.5-18.4), from 13 out-patient clinics and in healthy controls (n = 65), mean age 16.5 years (range: 15.9-17.7). HRV was registered in the sitting position during 4 min with no interventions. RESULTS: Logarithmically transformed high frequency HRV (HF), low frequency HRV (LF) and standard deviation of inter beat intervals (SDNN) were lower in the clinical sample compared with the controls (Cohen's d for HF = 0.57, LF = 0.55, SDNN = 0.60). This was not explained by body mass index, blood pressure or physical activity. Medication with SSRI explained 15.5% of the total variance of HF, 3.0% of LF and 6.5% of SDNN. CONCLUSIONS: Adolescent female psychiatric patients with AD and/or MDD show reduced HRV compared with healthy controls. Medication with SSRI explained a part of this difference.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Keyword
- Adolescent females
- Anxiety disorders
- Autonomic regulation
- Heart rate variability
- Major depressive disorder
- Selective serotonin reuptake inhibitors
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
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