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Genes predict villa...
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O'Dushlaine, Colm
(author)
Genes predict village of origin in rural Europe
- Article/chapterEnglish2010
Publisher, publication year, extent ...
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2010-06-23
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Springer Science and Business Media LLC,2010
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-133818
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-133818URI
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https://doi.org/10.1038/ejhg.2010.92DOI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30 km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals.
Subject headings and genre
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population structure
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principal components
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genome-wide genotyping
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MEDICINE
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MEDICIN
Added entries (persons, corporate bodies, meetings, titles ...)
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McQuillan, Ruth
(author)
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Weale, Michael E.
(author)
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Crouch, Daniel J. M.
(author)
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Johansson, ÅsaUppsala universitet,Institutionen för genetik och patologi(Swepub:uu)asjoh108
(author)
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Aulchenko, Yurii
(author)
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Franklin, Christopher S.
(author)
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Polasek, Ozren
(author)
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Fuchsberger, Christian
(author)
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Corvin, Aiden
(author)
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Hicks, Andrew A.
(author)
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Vitart, Veronique
(author)
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Hayward, Caroline
(author)
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Wild, Sarah H.
(author)
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Meitinger, Thomas
(author)
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van Duijn, Cornelia M.
(author)
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Gyllensten, UlfUppsala universitet,Institutionen för genetik och patologi(Swepub:uu)ulfgyll
(author)
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Wright, Alan F.
(author)
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Campbell, Harry
(author)
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Pramstaller, Peter P.
(author)
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Rudan, Igor
(author)
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Wilson, James F.
(author)
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Uppsala universitetInstitutionen för genetik och patologi
(creator_code:org_t)
Related titles
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In:European Journal of Human Genetics: Springer Science and Business Media LLC18:11, s. 1269-12701018-48131476-5438
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O'Dushlaine, Col ...
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McQuillan, Ruth
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Weale, Michael E ...
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Crouch, Daniel J ...
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Johansson, Åsa
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Aulchenko, Yurii
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show more...
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Franklin, Christ ...
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Polasek, Ozren
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Fuchsberger, Chr ...
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Corvin, Aiden
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Hicks, Andrew A.
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Vitart, Veroniqu ...
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Hayward, Carolin ...
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Wild, Sarah H.
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Meitinger, Thoma ...
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van Duijn, Corne ...
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Gyllensten, Ulf
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Wright, Alan F.
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Campbell, Harry
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Pramstaller, Pet ...
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Rudan, Igor
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Wilson, James F.
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Uppsala University