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  • O'Dushlaine, Colm (author)

Genes predict village of origin in rural Europe

  • Article/chapterEnglish2010

Publisher, publication year, extent ...

  • 2010-06-23
  • Springer Science and Business Media LLC,2010
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:uu-133818
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-133818URI
  • https://doi.org/10.1038/ejhg.2010.92DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30 km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals.

Subject headings and genre

  • population structure
  • principal components
  • genome-wide genotyping
  • MEDICINE
  • MEDICIN

Added entries (persons, corporate bodies, meetings, titles ...)

  • McQuillan, Ruth (author)
  • Weale, Michael E. (author)
  • Crouch, Daniel J. M. (author)
  • Johansson, ÅsaUppsala universitet,Institutionen för genetik och patologi(Swepub:uu)asjoh108 (author)
  • Aulchenko, Yurii (author)
  • Franklin, Christopher S. (author)
  • Polasek, Ozren (author)
  • Fuchsberger, Christian (author)
  • Corvin, Aiden (author)
  • Hicks, Andrew A. (author)
  • Vitart, Veronique (author)
  • Hayward, Caroline (author)
  • Wild, Sarah H. (author)
  • Meitinger, Thomas (author)
  • van Duijn, Cornelia M. (author)
  • Gyllensten, UlfUppsala universitet,Institutionen för genetik och patologi(Swepub:uu)ulfgyll (author)
  • Wright, Alan F. (author)
  • Campbell, Harry (author)
  • Pramstaller, Peter P. (author)
  • Rudan, Igor (author)
  • Wilson, James F. (author)
  • Uppsala universitetInstitutionen för genetik och patologi (creator_code:org_t)

Related titles

  • In:European Journal of Human Genetics: Springer Science and Business Media LLC18:11, s. 1269-12701018-48131476-5438

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