Search: onr:"swepub:oai:DiVA.org:uu-136377" >
The genome of a son...
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Warren, Wesley C
(author)
The genome of a songbird
- Article/chapterEnglish2010
Publisher, publication year, extent ...
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Springer Science and Business Media LLC,2010
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-136377
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-136377URI
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https://doi.org/10.1038/nature08819DOI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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The zebra finch is an important model organism in several fields with unique relevance to human neuroscience. Like other songbirds, the zebra finch communicates through learned vocalizations, an ability otherwise documented only in humans and a few other animals and lacking in the chicken-the only bird with a sequenced genome until now. Here we present a structural, functional and comparative analysis of the genome sequence of the zebra finch (Taeniopygia guttata), which is a songbird belonging to the large avian order Passeriformes. We find that the overall structures of the genomes are similar in zebra finch and chicken, but they differ in many intrachromosomal rearrangements, lineage-specific gene family expansions, the number of long-terminal-repeat-based retrotransposons, and mechanisms of sex chromosome dosage compensation. We show that song behaviour engages gene regulatory networks in the zebra finch brain, altering the expression of long non-coding RNAs, microRNAs, transcription factors and their targets. We also show evidence for rapid molecular evolution in the songbird lineage of genes that are regulated during song experience. These results indicate an active involvement of the genome in neural processes underlying vocal communication and identify potential genetic substrates for the evolution and regulation of this behaviour.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Clayton, David F
(author)
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Ellegren, HansUppsala universitet,Evolutionsbiologi(Swepub:uu)hanselle
(author)
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Arnold, Arthur P
(author)
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Hillier, Ladeana W
(author)
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Künstner, AxelUppsala universitet,Institutionen för ekologi och genetik
(author)
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Searle, Steve
(author)
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White, Simon
(author)
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Vilella, Albert J
(author)
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Fairley, Susan
(author)
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Heger, Andreas
(author)
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Kong, Lesheng
(author)
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Ponting, Chris P
(author)
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Jarvis, Erich D
(author)
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Mello, Claudio V
(author)
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Minx, Pat
(author)
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Lovell, Peter
(author)
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Velho, Tarciso A F
(author)
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Ferris, Margaret
(author)
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Balakrishnan, Christopher N
(author)
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Sinha, Saurabh
(author)
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Blatti, Charles
(author)
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London, Sarah E
(author)
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Li, Yun
(author)
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Lin, Ya-Chi
(author)
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George, Julia
(author)
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Sweedler, Jonathan
(author)
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Southey, Bruce
(author)
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Gunaratne, Preethi
(author)
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Watson, Michael
(author)
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Nam, KiwoongUppsala universitet,Institutionen för ekologi och genetik(Swepub:uu)kina356
(author)
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Backström, NiclasUppsala universitet,Institutionen för ekologi och genetik(Swepub:uu)nibac839
(author)
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Smeds, LinneaUppsala universitet,Institutionen för ekologi och genetik(Swepub:uu)linsm456
(author)
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Nabholz, BenoitUppsala universitet,Institutionen för ekologi och genetik
(author)
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Itoh, Yuichiro
(author)
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Whitney, Osceola
(author)
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Pfenning, Andreas R
(author)
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Howard, Jason
(author)
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Völker, Martin
(author)
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Skinner, Bejamin M
(author)
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Griffin, Darren K
(author)
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Ye, Liang
(author)
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McLaren, William M
(author)
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Flicek, Paul
(author)
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Quesada, Victor
(author)
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Velasco, Gloria
(author)
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Lopez-Otin, Carlos
(author)
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Puente, Xose S
(author)
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Olender, Tsviya
(author)
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Lancet, Doron
(author)
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Smit, Arian F A
(author)
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Hubley, Robert
(author)
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Konkel, Miriam K
(author)
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Walker, Jerilyn A
(author)
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Batzer, Mark A
(author)
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Gu, Wanjun
(author)
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Pollock, David D
(author)
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Chen, Lin
(author)
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Cheng, Ze
(author)
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Eichler, Evan E
(author)
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Stapley, Jessica
(author)
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Slate, Jon
(author)
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Ekblom, Robert
(author)
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Birkhead, Tim
(author)
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Burke, Terry
(author)
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Burt, David
(author)
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Scharff, Constance
(author)
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Adam, Iris
(author)
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Richard, Hugues
(author)
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Sultan, Marc
(author)
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Soldatov, Alexey
(author)
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Lehrach, Hans
(author)
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Edwards, Scott V
(author)
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Yang, Shiaw-Pyng
(author)
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Li, Xiaoching
(author)
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Graves, Tina
(author)
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Fulton, Lucinda
(author)
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Nelson, Joanne
(author)
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Chinwalla, Asif
(author)
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Hou, Shunfeng
(author)
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Mardis, Elaine R
(author)
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Wilson, Richard K
(author)
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Uppsala universitetEvolutionsbiologi
(creator_code:org_t)
Related titles
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In:Nature: Springer Science and Business Media LLC464:7289, s. 757-7620028-08361476-4687
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To the university's database
- By the author/editor
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Warren, Wesley C
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Clayton, David F
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Ellegren, Hans
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Arnold, Arthur P
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Hillier, Ladeana ...
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Künstner, Axel
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show more...
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Searle, Steve
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White, Simon
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Vilella, Albert ...
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Fairley, Susan
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Heger, Andreas
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Kong, Lesheng
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Ponting, Chris P
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Jarvis, Erich D
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Mello, Claudio V
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Minx, Pat
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Lovell, Peter
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Velho, Tarciso A ...
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Ferris, Margaret
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Balakrishnan, Ch ...
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Sinha, Saurabh
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Blatti, Charles
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London, Sarah E
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Li, Yun
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Lin, Ya-Chi
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George, Julia
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Sweedler, Jonath ...
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Southey, Bruce
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Gunaratne, Preet ...
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Watson, Michael
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Nam, Kiwoong
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Backström, Nicla ...
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Smeds, Linnea
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Nabholz, Benoit
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Itoh, Yuichiro
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Whitney, Osceola
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Pfenning, Andrea ...
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Howard, Jason
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Völker, Martin
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Skinner, Bejamin ...
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Griffin, Darren ...
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Ye, Liang
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McLaren, William ...
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Flicek, Paul
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Quesada, Victor
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Velasco, Gloria
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Lopez-Otin, Carl ...
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Puente, Xose S
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Olender, Tsviya
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Lancet, Doron
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Smit, Arian F A
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Hubley, Robert
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Konkel, Miriam K
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Walker, Jerilyn ...
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Batzer, Mark A
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Gu, Wanjun
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Pollock, David D
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Chen, Lin
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Cheng, Ze
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Eichler, Evan E
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Stapley, Jessica
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Slate, Jon
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Ekblom, Robert
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Birkhead, Tim
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Burke, Terry
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Burt, David
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Scharff, Constan ...
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Adam, Iris
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Richard, Hugues
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Sultan, Marc
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Soldatov, Alexey
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Lehrach, Hans
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Edwards, Scott V
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Yang, Shiaw-Pyng
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Li, Xiaoching
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Graves, Tina
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Fulton, Lucinda
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Nelson, Joanne
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Chinwalla, Asif
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Hou, Shunfeng
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Mardis, Elaine R
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Wilson, Richard ...
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- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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Nature
- By the university
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Uppsala University