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Physical capacity, ...
Physical capacity, respiratory quotient and energy expenditure during exercise in male patients with schizophrenia compared with healthy controls
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- Nilsson, Björn Mikael (author)
- Uppsala universitet,Psykiatri, Akademiska sjukhuset
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- Olsson, Roger M. (author)
- Uppsala universitet,Klinisk nutrition och metabolism
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- Öman, Anders (author)
- Uppsala universitet,Institutionen för kvinnors och barns hälsa,Perinatal, neonatal och barnkardiologisk forskning/Jonzon
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- Wiesel, Frits-Axel (author)
- Uppsala universitet,Psykiatri, Akademiska sjukhuset
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- Ekselius, Lisa (author)
- Uppsala universitet,Psykiatri, Akademiska sjukhuset
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- Forslund, Anders H. (author)
- Uppsala universitet,Klinisk nutrition och metabolism,Institutionen för kvinnors och barns hälsa,Barnendokrinologisk forskning/Gustafsson
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(creator_code:org_t)
- 2020-04-15
- 2012
- English.
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In: European psychiatry. - : Cambridge University Press (CUP). - 0924-9338 .- 1778-3585. ; 27:3, s. 206-212
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- BACKGROUND Despite massive research on weight gain and metabolic complications in schizophrenia there are few studies on energy expenditure and no current data on physical capacity. AIM: To determine oxygen uptake capacity, respiratory quotient (RQ) and energy expenditure during a submaximal exercise test in patients with schizophrenia and healthy controls. METHOD Ten male patients and 10 controls were included. RQ and energy expenditure were investigated with indirect calorimetry during a cycle ergometer test. The submaximal work level was defined by heart rate and perceived exhaustion. Physical capacity was determined from predicted maximal oxygen uptake capacity (VO(2-max)). RESULTS The patients exhibited significantly higher RQ on submaximal workloads and lower physical capacity. A significant lower calculated VO(2-max) remained after correction for body weight and fat free mass (FFM). Energy expenditure did not differ on fixed workloads. CONCLUSION RQ was rapidly increasing in the patients during exercise indicating a faster transition to carbohydrate oxidation and anaerobic metabolism that also implies a performance closer to maximal oxygen uptake even at submaximal loads. This may restrict the capacity for everyday activity and exercise and thus contribute to the risk for weight gain. Physical capacity was consequently significantly lower in the patients.
Keyword
- Schizophrenia
- Physical capacity
- Respiratory quotient
- Oxygen uptakecapacity
- Energy expenditure
- Body weight
Publication and Content Type
- ref (subject category)
- art (subject category)
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