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Interaction between...
Interaction between amphiphilic peptides and phospholipid membranes
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- Strömstedt, Adam A. (author)
- Uppsala universitet,Institutionen för farmaci
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- Ringstad, Lovisa (author)
- Uppsala universitet,Institutionen för farmaci
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- Schmidtchen, Artur (author)
- Lund University,Lunds universitet,Dermatologi och venereologi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Dermatology and Venereology (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Malmsten, Martin (author)
- Uppsala University,Uppsala universitet,Institutionen för farmaci
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(creator_code:org_t)
- Elsevier BV, 2010
- 2010
- English.
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In: Current Opinion in Colloid & Interface Science. - : Elsevier BV. - 1359-0294 .- 1879-0399. ; 15:6, s. 467-478
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Abstract
Subject headings
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- This brief review aims at providing some illustrative examples on the interaction between amphiphilic peptides and phospholipid membranes an area of significant current interest Focusing on antimicrobial peptides factors affecting peptide-membrane interactions are addressed including effects of peptide length charge hydrophobicity secondary structure and topology Effects of membrane composition are also illustrated including effects of membrane charge nature of the polar headgroup and presence of cholesterol and other sterols Throughout novel insights on the importance of peptide adsorption density on membrane stability are emphasized as is the correlation between peptide adsorption peptide induced leakage in model liposome systems peptide-induced lysis of bacteria and bacteria killing.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmaceutiska vetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmaceutical Sciences (hsv//eng)
- NATURVETENSKAP -- Kemi -- Fysikalisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Physical Chemistry (hsv//eng)
Keyword
- AMP
- Antimicrobial peptide
- Bacteria
- Liposome
- Membrane
- PHARMACY
- FARMACI
- Liposome
- Bacteria
- AMP
- Antimicrobial peptide
- Membrane
Publication and Content Type
- ref (subject category)
- for (subject category)
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