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The MHC class II of...
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Strand, TanjaUppsala universitet,Populationsbiologi och naturvårdsbiologi
(author)
The MHC class II of the Black grouse (Tetrao tetrix) consists of low numbers of B and Y genes with variable diversity and expression
- Article/chapterEnglish2007
Publisher, publication year, extent ...
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2007-07-25
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Springer Science and Business Media LLC,2007
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-14669
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-14669URI
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https://doi.org/10.1007/s00251-007-0234-6DOI
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https://lup.lub.lu.se/record/657339URI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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We found that the Black grouse (Tetrao tetrix) possess low numbers of Mhc class II B (BLB) and Y (YLB) genes with variable diversity and expression. We have therefore shown, for the first time, that another bird species (in this case, a wild lek-breeding galliform) shares several features of the simple Mhc of the domestic chicken (Gallus gallus). The Black grouse BLB genes showed the same level of polymorphism that has been reported in chicken, and we also found indications of balancing selection in the peptide-binding regions. The YLB genes were less variable than the BLB genes, also in accordance with earlier studies in chicken, although their functional significance still remains obscure. We hypothesize that the YLB genes could have been under purifying selection, just as the mammal Mhc-E gene cluster.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Westerdahl, HelenaLund University,Lunds universitet,MEMEG,Biologiska institutionen,Naturvetenskapliga fakulteten,Department of Biology,Faculty of Science(Swepub:lu)ekol-hwe
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Höglund, JacobUppsala universitet,Populationsbiologi och naturvårdsbiologi(Swepub:uu)jacohogl
(author)
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Alatalo, Rauno V.
(author)
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Siitari, Heli
(author)
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Uppsala universitetPopulationsbiologi och naturvårdsbiologi
(creator_code:org_t)
Related titles
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In:Immunogenetics: Springer Science and Business Media LLC59:9, s. 725-7340093-77111432-1211
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