SwePub
Sök i LIBRIS databas

  Extended search

onr:"swepub:oai:DiVA.org:uu-148646"
 

Search: onr:"swepub:oai:DiVA.org:uu-148646" > Smokers and non-smo...

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Smokers and non-smokers with rheumatoid arthritis have similar clinical status : data from the multinational QUEST-RA database

Naranjo, A. (author)
Toloza, S. (author)
Guimaraes da Silveira, I. (author)
show more...
Lazovskis, J. (author)
Hetland, M. L. (author)
Hamoud, H. (author)
Peets, T. (author)
Makinen, H. (author)
Gossec, L. (author)
Herborn, G. (author)
Skopouli, F. N. (author)
Rojkovich, B. (author)
Aggarwal, A. (author)
Minnock, P. (author)
Cazzato, M. (author)
Yamanaka, H. (author)
Oyoo, O. (author)
Rexhepi, S. (author)
Andersone, D. (author)
Baranauskaite, A. (author)
Hajjaj-Hassouni, N. (author)
Jacobs, J. W. G. (author)
Haugeberg, G. (author)
Sierakowski, S. (author)
Ionescu, R. (author)
Karateew, D. (author)
Dimic, A. (author)
Henrohn, Dan (author)
Uppsala universitet,Institutionen för farmaceutisk biovetenskap,Biologisk beroendeforskning
Gogus, F. (author)
Badsha, H. (author)
Choy, E. (author)
Bergman, M. (author)
Sokka, T. (author)
show less...
 (creator_code:org_t)
2010
2010
English.
In: Clinical and Experimental Rheumatology. - 0392-856X .- 1593-098X. ; 28:6, s. 820-827
Related links:
https://urn.kb.se/re...
  • Journal article (peer-reviewed)
Abstract Subject headings
Close  
  • Objectives To analyse clinical severity/activity of rheumatoid arthritis (RA) according to smoking status. Methods The QUEST-RA multinational database reviews patients for Core Data Set measures including 28 swollen and tender joint count, physician global estimate, erythrocyte sedimentation rate (ESR), HAQ-function, pain, and patient global estimate, as well as DAS28, rheumatoid factor (RE), nodules, erosions and number of DMARDs were recorded. Smoking status was assessed by self-report as "never smoked", "currently smoking" and "former smokers". Patient groups with different smoking status were compared for demographic and RA measures. Results Among the 7,307 patients with smoking data available, status as "never smoked," "current smoker" and "former smoker" were reported by 65%, 15% and 20%. Ever smokers were more likely to be RF-positive (OR 1.32; 1.17-1.48, p<0.001). Rheumatoid nodules were more frequent in ever smokers (OR 1.41; 1.24-1.59, p<0.001). The percentage of patients with erosive arthritis and extra-articular disease was similar in all smoking categories. Mean DAS28 was 4.4 (SD 1.6) in non-smokers vs. 4.0 (SD 1.6) in those who had ever smoked. However, when adjusted by age, sex, disease duration, and country gross domestic product, only ESR remained significantly different among Core Data Set measures (mean 31.7mm in non-smokers vs. 26.8mm in ever smoked category). Conclusion RA patients who had ever smoked were more likely to have RF and nodules, hut values for other clinical status measures were similar in all smoking categories (never smoked, current smokers and former smokers).

Keyword

rheumatoid arthritis
smoking
HAQ
DAS
MEDICINE
MEDICIN

Publication and Content Type

ref (subject category)
art (subject category)

Find in a library

To the university's database

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view