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  • Li, Yan (author)

Is blood pressure during the night more predictive of cardiovascular outcome than during the day?

  • Article/chapterEnglish2008

Publisher, publication year, extent ...

  • 2008
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:uu-149662
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-149662URI
  • https://doi.org/10.1097/MBP.0b013e3282fd16ccDOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Group Author(s): Int Database Ambulatory Blood Pre; Cardiovas Outcomes Investigators
  • The objective of this study was to investigate the prognostic significance of the ambulatory blood pressure (BP) during night and day and of the night-to-day BP ratio (NDR). We studied 7458 participants (mean age 56.8 years; 45.8% women) enrolled in the International Database on Ambulatory BP in relation to Cardiovascular Outcome. Using Cox models, we calculated hazard ratios (HR) adjusted for cohort and cardiovascular risk factors. Over 9.6 years (median), 983 deaths and 943 cardiovascular events occurred. Nighttime BP predicted mortality outcomes (HR, 1.18-1.24; P<0.01) independent of daytime BP. Conversely, daytime systolic (HR, 0.84; P<0.01) and diastolic BP (HR, 0.88; P<0.05) predicted only noncardiovascular mortality after adjustment for nighttime BR Both daytime BP and nighttime BP consistently predicted all cardiovascular events (HR, 1.11-1.33, P<0.05) and stroke (HR, 1.21-1.47; P<0.01). Daytime BP lost its prognostic significance for cardiovascular events in patients on antihypertensive treatment. Adjusted for the 24-h BP, NDR predicted mortality (P<0.05), but not fatal combined with nonfatal events. Participants with systolic NDR of at least 1 compared with participants with normal NDR (>= 0.80 to < 0.90) were older, at higher risk of death, but died at higher age. The predictive accuracy of the daytime and nighttime BP and the NDR depended on the disease outcome under study. The increased mortality in patients with higher NDR probably indicates reverse causality. Our findings support recording the ambulatory BP during the whole day.

Subject headings and genre

  • ambulatory blood pressure monitoring
  • blood pressure
  • cardiovascular outcome
  • MEDICINE
  • MEDICIN

Added entries (persons, corporate bodies, meetings, titles ...)

  • Boggia, Jose (author)
  • Thijs, Lutgarde (author)
  • Hansen, Tine W. (author)
  • Kikuya, Masahiro (author)
  • Björklund-Bodegård, KristinaUppsala universitet,Geriatrik(Swepub:uu)krisbjor (author)
  • Richart, Tom (author)
  • Ohkubo, Takayoshi (author)
  • Kuznetsova, Tatiana (author)
  • Torp-Pedersen, Christian (author)
  • Lind, LarsUppsala universitet,Geriatrik(Swepub:uu)larslind (author)
  • Ibsen, Hans (author)
  • Imai, Yutaka (author)
  • Wang, Jiguang (author)
  • Sandoya, Edgardo (author)
  • O'Brieni, Eoin (author)
  • Staessen, Jan A. (author)
  • Uppsala universitetGeriatrik (creator_code:org_t)

Related titles

  • In:Blood Pressure Monitoring13:3, s. 145-1471359-52371473-5725

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