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Services for predic...
Services for prediction of drug susceptibility for HIV proteases and reverse transcriptases at the HIV Drug Research Centre
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- Spjuth, Ola, 1977- (author)
- Uppsala universitet,Institutionen för farmaceutisk biovetenskap
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- Eklund, Martin, 1978- (author)
- Uppsala universitet,Institutionen för farmaceutisk biovetenskap
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- Lapins, Maris (author)
- Uppsala universitet,Institutionen för farmaceutisk biovetenskap
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- Junaid, Muhammad (author)
- Uppsala universitet,Institutionen för farmaceutisk biovetenskap
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- Wikberg, Jarl (author)
- Uppsala universitet,Institutionen för farmaceutisk biovetenskap
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(creator_code:org_t)
- 2011-04-14
- 2011
- English.
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In: Bioinformatics. - Oxford : Oxford University Press. - 1367-4803 .- 1367-4811. ; 27:12, s. 1719-1720
- Related links:
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https://academic.oup...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Summary: The HIV Drug Research Centre (HIVDRC) has established Web services for prediction of drug susceptibility for HIV proteases and reverse transcriptases. The services are based on two proteochemometric models which accepts a protease or reverse transcriptase sequence in amino acid form, and outputs the predicted drug susceptibility values. The predictions are based on a comprehensive analysis where all the relevant inhibitors are included, resulting in models with excellent predictive capabilities.Availability and Implementation: The services are implemented as interoperable Web services (REST and XMPP), with supporting web pages to allow for individual analyses. A set of plugins were also developed which make the services available from the Bioclipse workbench for life science. Services are available athttp://www.hivdrc.org/services.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)
Keyword
- hiv
- bioclipse
- susceptibility
- services
- Pharmacology
- Farmakologi
- Bioinformatik
- Bioinformatics
Publication and Content Type
- ref (subject category)
- art (subject category)
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