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Practical recommend...
Practical recommendations for pharmacogenomics-based prescription : 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics
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Becquemont, Laurent (author)
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Alfirevic, Ana (author)
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Amstutz, Ursula (author)
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Brauch, Hiltrud (author)
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Jacqz-Aigrain, Evelyne (author)
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Laurent-Puig, Pierre (author)
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Molina, Miguel A (author)
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Niemi, Mikko (author)
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Schwab, Matthias (author)
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Somogyi, Andrew A (author)
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Thervet, Eric (author)
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Maitland-van der Zee, Anke-Hilse (author)
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van Kuilenburg, André Bp (author)
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van Schaik, Ron Hn (author)
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Verstuyft, Céline (author)
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- Wadelius, Mia (author)
- Uppsala universitet,Klinisk farmakogenomik och osteoporos,Clinical pharmacogenomics
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Daly, Ann K (author)
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(creator_code:org_t)
- Future Medicine Ltd, 2011
- 2011
- English.
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In: Pharmacogenomics (London). - : Future Medicine Ltd. - 1462-2416 .- 1744-8042. ; 12:1, s. 113-124
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https://urn.kb.se/re...
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https://doi.org/10.2...
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Abstract
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- The present article summarizes the discussions of the 3rd European Science Foundation-University of Barcelona (ESF-UB) Conference in Biomedicine on Pharmacogenetics and Pharmacogenomics, which was held in June 2010 in Spain. It was focused on practical applications in routine medical practice. We provide practical recommendations for ten different clinical situations, that have either been approved or not approved by regulatory agencies. We propose some comments that might accompany the results of these tests, indicating the best drug and doses to be prescribed. The discussed examples include KRAS, cetuximab, panitumumab, EGFR-gefitinib, CYP2D6-tamoxifen, TPMT-azathioprine-6-mercaptopurine, VKORC1/CYP2C9-warfarin, CYP2C19-clopidogrel, HLA-B*5701-abacavir, HLA-B*5701-flucloxacillin, SLCO1B1-statins and CYP3A5-tacrolimus. We hope that these practical recommendations will help physicians, biologists, scientists and other healthcare professionals to prescribe, perform and interpret these genetic tests.
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- MEDICINE
- MEDICIN
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- By the author/editor
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Becquemont, Laur ...
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Alfirevic, Ana
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Amstutz, Ursula
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Brauch, Hiltrud
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Jacqz-Aigrain, E ...
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Laurent-Puig, Pi ...
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show more...
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Molina, Miguel A
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Niemi, Mikko
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Schwab, Matthias
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Somogyi, Andrew ...
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Thervet, Eric
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Maitland-van der ...
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van Kuilenburg, ...
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van Schaik, Ron ...
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Verstuyft, Célin ...
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Wadelius, Mia
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Daly, Ann K
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show less...
- Articles in the publication
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Pharmacogenomics ...
- By the university
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Uppsala University