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No benefit of treat...
No benefit of treatment with cyclophosphamide and autologous blood stem cell transplantation in multifocal motor neuropathy
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- Axelson, Hans W. (author)
- Uppsala universitet,Klinisk neurofysiologi
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- Öberg, Gunnar (author)
- Uppsala universitet,Institutionen för medicinska vetenskaper
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- Askmark, Håkan (author)
- Uppsala universitet,Neurologi
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(creator_code:org_t)
- 2007-12-12
- 2008
- English.
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In: Acta Neurologica Scandinavica. - : Hindawi Limited. - 0001-6314 .- 1600-0404. ; 117:6, s. 432-434
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Abstract
Subject headings
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- Introduction - Patients with multifocal motor neuropathy (MMN) usually respond to intravenous immunoglobulin (IVIG), but because of the short-lasting effect the treatment must be given repeatedly. Remission after treatment with high-dose cyclophosphamide has recently been reported in one patient refractory to IVIG. Case report - Here we report on a patient who responded to IVIG, but temporarily deteriorated dramatically after treatment with high-dose cyclophosphamide and autologous blood stem cell transplantation. Today the situation is the same as before the treatment with cyclophosphamide and blood stem cell transplantation, i.e. IVIG is given every 4 weeks. Conclusion - Our patient did not benefit from the treatment with high-dose cyclophosphamide and autologous blood stem cell transplantation. The effect of treatment with high-dose cyclophosphamide in MMN seems to be difficult to predict and that should be paid attention to if this type of treatment is considered.
Keyword
- multifocal motor neuropathy
- MMN
- treatment
- cyclophosphamide
- blood stem cell transplantation
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
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