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Single-fiber conduc...
Single-fiber conduction velocity test allows earlier detection of abnormalities in diabetes
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Padua, Luca (author)
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- Stålberg, Erik (author)
- Uppsala universitet,Klinisk neurofysiologi
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Caliandro, Pietro (author)
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Muscogiuri, Giovanna (author)
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Pazzaglia, Costanza (author)
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Sorice, Gian Pio (author)
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Granata, Giuseppe (author)
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Salomone, Enrica (author)
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Pontecorvi, Alfredo (author)
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Giaccari, Andrea (author)
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(creator_code:org_t)
- 2011-04-11
- 2011
- English.
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In: Muscle and Nerve. - : Wiley. - 0148-639X .- 1097-4598. ; 43:5, s. 652-656
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Introduction: The purpose of this study was to determine whether single-fiber conduction velocity (SF-CV) of a small number of axons increases sensitivity for identification of motor nerve conduction alterations in patients with diabetes. Methods: Twenty-one consecutive diabetic patients in good metabolic control were studied. For each patient, conventional (C-CV) and SF-CV results were correlated with the presence of neuropathic symptoms. Results: Nine of 21 patients reported symptoms suggestive of mild nerve impairment. Three patients had abnormal sural nerve CV, 1 of whom also had abnormal motor nerve conduction. Eighteen patients had normal findings on conventional tests, 3 of whom had slowing of SF-CV. Conclusions: SF-CV is able to detect mild myelin damage with higher sensitivity than conventional tests. The use of SF-CV may be a helpful tool in the early identification of diabetic polyneuropathy, and it may be useful for tailoring an approach to diabetic polyneuropathy.
Keyword
- diabetes
- diabetic polyneuropathy
- electrodiagnosis
- neurophysiology
- SFEMG
- single-fiber conduction velocity
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Padua, Luca
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Stålberg, Erik
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Caliandro, Pietr ...
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Muscogiuri, Giov ...
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Pazzaglia, Costa ...
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Sorice, Gian Pio
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show more...
-
Granata, Giusepp ...
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Salomone, Enrica
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Pontecorvi, Alfr ...
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Giaccari, Andrea
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show less...
- Articles in the publication
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Muscle and Nerve
- By the university
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Uppsala University