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Whole-genome shotgu...
Whole-genome shotgun sequencing of mitochondria from ancient hair shafts
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Gilbert, M. Thomas P. (author)
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Tomsho, Lynn P. (author)
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Rendulic, Snjezana (author)
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Packard, Michael (author)
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Drautz, Daniela I. (author)
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Sher, Andrei (author)
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Tikhonov, Alexei (author)
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- Dalén, Love (author)
- Naturhistoriska riksmuseet,Enheten för bioinformatik och genetik
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Kuznetsova, Tatyana (author)
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Kosintsev, Pavel (author)
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Campos, Paula F. (author)
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Higham, Thomas (author)
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Collins, Matthew J. (author)
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Wilson, Andrew S. (author)
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Shidlovskiy, Fyodor (author)
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Buigues, Bernard (author)
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- Ericson, Per G P, 1956- (author)
- Naturhistoriska riksmuseet,Forskningsavdelningen centralt
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Germonpré, Mietje (author)
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- Götherström, Anders (author)
- Uppsala universitet,Evolutionsbiologi,Ancient DNA
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Iacumin, Paola (author)
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Nikolaev, Vladimir (author)
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Nowak-Kemp, Malgosia (author)
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Willerslev, Eske (author)
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Knight, James R. (author)
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Irzyk, Gerard P. (author)
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Perbost, Clotilde S. (author)
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Fredrikson, Karin M. (author)
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Harkins, Timothy T. (author)
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Sheridan, Sharon (author)
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Miller, Webb (author)
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Schuster, Stephan C. (author)
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(creator_code:org_t)
- American Association for the Advancement of Science (AAAS), 2007
- 2007
- English.
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In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 317:5846, s. 1927-1930
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Subject headings
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- Although the application of sequencing-by-synthesis techniques to DNA extracted from bones has revolutionized the study of ancient DNA, it has been plagued by large fractions of contaminating environmental DNA. The genetic analyses of hair shafts could be a solution: We present 10 previously unexamined Siberian mammoth (Mammuthus primigenius) mitochondrial genomes, sequenced with up to 48-fold coverage. The observed levels of damage-derived sequencing errors were lower than those observed in previously published frozen bone samples, even though one of the specimens was >50,000 14C years old and another had been stored for 200 years at room temperature. The method therefore sets the stage for molecular-genetic analysis of museum collections.
Subject headings
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
- NATURVETENSKAP -- Biologi -- Evolutionsbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Evolutionary Biology (hsv//eng)
Keyword
- Biology
- Biologi
- Livets mångfald
Publication and Content Type
- ref (subject category)
- art (subject category)
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Science
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To the university's database
- By the author/editor
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Gilbert, M. Thom ...
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Tomsho, Lynn P.
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Rendulic, Snjeza ...
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Packard, Michael
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Drautz, Daniela ...
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Sher, Andrei
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show more...
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Tikhonov, Alexei
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Dalén, Love
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Kuznetsova, Taty ...
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Kosintsev, Pavel
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Campos, Paula F.
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Higham, Thomas
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Collins, Matthew ...
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Wilson, Andrew S ...
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Shidlovskiy, Fyo ...
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Buigues, Bernard
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Ericson, Per G P ...
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Germonpré, Mietj ...
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Götherström, And ...
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Iacumin, Paola
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Nikolaev, Vladim ...
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Nowak-Kemp, Malg ...
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Willerslev, Eske
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Knight, James R.
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Irzyk, Gerard P.
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Perbost, Clotild ...
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Fredrikson, Kari ...
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Harkins, Timothy ...
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Sheridan, Sharon
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Miller, Webb
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Schuster, Stepha ...
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show less...
- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Evolutionary Bio ...
- Articles in the publication
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Science
- By the university
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Uppsala University
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Swedish Museum of Natural History