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  • de la Torre, Teresa Zardan GomezUppsala universitet,Nanoteknologi och funktionella material (author)

Molecular diagnostics using magnetic nanobeads

  • Article/chapterEnglish2010

Publisher, publication year, extent ...

  • 2010-02-15
  • IOP Publishing,2010
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:uu-155696
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-155696URI
  • https://doi.org/10.1088/1742-6596/200/12/122011DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:kon swepub-publicationtype

Series

  • Journal of Physics: Conference Series,1742-6588 ;200

Notes

  • In this paper, we investigate the volume-amplified magnetic nanobead detection assay with respect to bead size, bead concentration and bead oligonucleotide surface coverage in order to improve the understanding of the underlying microscopic mechanisms. It has been shown that: (i) the immobilization efficiency of the beads depends on the surface coverage of oligonucleotides, (ii) by using lower amounts of probe-tagged beads, detection sensitivity can be improved and (iii) using small enough beads enables both turn-off and turn-on detection. Finally, biplex detection was demonstrated.

Subject headings and genre

  • NATURAL SCIENCES
  • NATURVETENSKAP

Added entries (persons, corporate bodies, meetings, titles ...)

  • Strömberg, MattiasUppsala universitet,Nanoteknologi och funktionella material(Swepub:uu)makar103 (author)
  • Göransson, Jenny (author)
  • Gunnarsson, KlasUppsala universitet,Fasta tillståndets fysik(Swepub:uu)klgun011 (author)
  • Nilsson, MatsUppsala universitet,Molekylära verktyg(Swepub:uu)matsnils (author)
  • Svedlindh, PeterUppsala universitet,Fasta tillståndets fysik(Swepub:uu)petesved (author)
  • Strømme, MariaUppsala universitet,Nanoteknologi och funktionella material(Swepub:uu)mst26208 (author)
  • Uppsala universitetNanoteknologi och funktionella material (creator_code:org_t)

Related titles

  • In:Journal of Physics: Conference Series: IOP Publishing1742-6596

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