Pregnancy and risk of acute myeloid leukaemia: a case-control study

Pregnancy and risk of acute myeloid leukaemia : a case-control study

Larfors, Gunnar (author): Karolinska Institutet,Uppsala universitet,Hematologi

(creator_code:org_t)

2011-07-15
2011
English.
In: European Journal of Haematology. - : Wiley. - 0902-4441 .- 1600-0609. ; 87:2, s. 169-171

Related links:: https://urn.kb.se/re...; show more...; https://doi.org/10.1...; http://kipublication...; show less...

Abstract Subject headings

Although maternal haematopoiesis is characterised by rapid proliferation and immunological adjustment, leukaemia seldom occurs in pregnant women. In this case-control study, we investigated pregnancy and risk of acute myeloid leukaemia (AML). A total of 785 women with AML diagnosed in ages 15-50 were compared with 1576 age-and sex-matched controls. At the time of diagnosis, 13 cases and 53 controls were pregnant (1.3% and 3.4%, respectively), resulting in a significantly reduced odds ratio of 0.44 (95% confidence interval 0.22-0.85). Odds ratios of AML during the years following childbirth were close to unity. The results suggest that pregnancy conveys a strong short-term protection against AML.

By the author/editor: Larfors, Gunnar; Höglund, Martin; Cnattingius, Sve ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Hematology

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.