Search: onr:"swepub:oai:DiVA.org:uu-156609" >
Are liver function ...
Are liver function tests, pancreatitis and cholecystitis predictors of common bile duct stones? : Results of a prospective, population-based, cohort study of 1171 patients undergoing cholecystectomy
-
Videhult, Per (author)
-
- Sandblom, Gabriel (author)
- Karolinska Institutet
-
- Rudberg, Claes (author)
- Uppsala universitet,Centrum för klinisk forskning, Västerås
-
show more...
-
- Rasmussen, Ib Christian (author)
- Uppsala universitet,Gastrointestinalkirurgi
-
show less...
-
(creator_code:org_t)
- Elsevier BV, 2011
- 2011
- English.
-
In: HPB. - : Elsevier BV. - 1365-182X .- 1477-2574. ; 13:8, s. 519-527
- Related links:
-
http://www.hpbonline...
-
show more...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
http://kipublication...
-
show less...
Abstract
Subject headings
Close
- Objective: The purpose of this study was to explore the accuracy of elevated liver function values, age, gender, pancreatitis and cholecystitis as predictors of common bile duct stones (CBDS). Methods: All patients operated on for gallstone disease over a period of 3 years in a Swedish county of 302 564 citizens were registered prospectively. Intraoperative cholangiography (IOC) was used to detect CBDS. Results: A total of 1171 patients were registered; 95% of these patients underwent IOC. Common bile duct stones were found in 42% of patients with elevated liver function values, 20% of patients with a history of pancreatitis and 9% of patients with cholecystitis. The presence of CBDS was significantly predicted by elevated liver function values, but not by age, gender, history of acute pancreatitis or cholecystitis. A total of 93% of patients with normal liver function tests had a normal IOC. The best agreement between elevated liver function values and CBDS was seen in patients undergoing elective surgery without a history of acute pancreatitis or cholecystitis. Conclusions: Although alkaline phosphatase (ALP) and bilirubin levels represented the most reliable predictors of CBDS, false positive and false negative values were common, especially in patients with a history of cholecystitis or pancreatitis, which indicates that other mechanisms were responsible for elevated liver function values in these patients.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Keyword
- prediction
- common bile duct stones
- alkaline phosphatase (ALP)
- bilirubin
- gallstone disease
- cholecystectomy
- dynamic intraoperative cholangiography
- prospective population-based study
- pancreatitis
- cholecystitis
- Surgery
- Kirurgi
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
-
HPB
(Search for host publication in LIBRIS)
To the university's database