Search: onr:"swepub:oai:DiVA.org:uu-157843" >
Comparative genomic...
Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium.
- Article/chapterEnglish2010
Publisher, publication year, extent ...
-
Springer Science and Business Media LLC,2010
-
printrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:uu-157843
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-157843URI
-
https://doi.org/10.1038/nature08850DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
Fusarium species are among the most important phytopathogenic and toxigenic fungi. To understand the molecular underpinnings of pathogenicity in the genus Fusarium, we compared the genomes of three phenotypically diverse species: Fusarium graminearum, Fusarium verticillioides and Fusarium oxysporum f. sp. lycopersici. Our analysis revealed lineage-specific (LS) genomic regions in F. oxysporum that include four entire chromosomes and account for more than one-quarter of the genome. LS regions are rich in transposons and genes with distinct evolutionary profiles but related to pathogenicity, indicative of horizontal acquisition. Experimentally, we demonstrate the transfer of two LS chromosomes between strains of F. oxysporum, converting a non-pathogenic strain into a pathogen. Transfer of LS chromosomes between otherwise genetically isolated strains explains the polyphyletic origin of host specificity and the emergence of new pathogenic lineages in F. oxysporum. These findings put the evolution of fungal pathogenicity into a new perspective.
Added entries (persons, corporate bodies, meetings, titles ...)
-
van der Does, H Charlotte
(author)
-
Borkovich, Katherine A
(author)
-
Coleman, Jeffrey J
(author)
-
Daboussi, Marie-Josée
(author)
-
Di Pietro, Antonio
(author)
-
Dufresne, Marie
(author)
-
Freitag, Michael
(author)
-
Grabherr, Manfred
(author)
-
Henrissat, Bernard
(author)
-
Houterman, Petra M
(author)
-
Kang, Seogchan
(author)
-
Shim, Won-Bo
(author)
-
Woloshuk, Charles
(author)
-
Xie, Xiaohui
(author)
-
Xu, Jin-Rong
(author)
-
Antoniw, John
(author)
-
Baker, Scott E
(author)
-
Bluhm, Burton H
(author)
-
Breakspear, Andrew
(author)
-
Brown, Daren W
(author)
-
Butchko, Robert A E
(author)
-
Chapman, Sinead
(author)
-
Coulson, Richard
(author)
-
Coutinho, Pedro M
(author)
-
Danchin, Etienne G J
(author)
-
Diener, Andrew
(author)
-
Gale, Liane R
(author)
-
Gardiner, Donald M
(author)
-
Goff, Stephen
(author)
-
Hammond-Kosack, Kim E
(author)
-
Hilburn, Karen
(author)
-
Hua-Van, Aurélie
(author)
-
Jonkers, Wilfried
(author)
-
Kazan, Kemal
(author)
-
Kodira, Chinnappa D
(author)
-
Koehrsen, Michael
(author)
-
Kumar, Lokesh
(author)
-
Lee, Yong-Hwan
(author)
-
Li, Liande
(author)
-
Manners, John M
(author)
-
Miranda-Saavedra, Diego
(author)
-
Mukherjee, Mala
(author)
-
Park, Gyungsoon
(author)
-
Park, Jongsun
(author)
-
Park, Sook-Young
(author)
-
Proctor, Robert H
(author)
-
Regev, Aviv
(author)
-
Ruiz-Roldan, M Carmen
(author)
-
Sain, Divya
(author)
-
Sakthikumar, Sharadha
(author)
-
Sykes, Sean
(author)
-
Schwartz, David C
(author)
-
Turgeon, B Gillian
(author)
-
Wapinski, Ilan
(author)
-
Yoder, Olen
(author)
-
Young, Sarah
(author)
-
Zeng, Qiandong
(author)
-
Zhou, Shiguo
(author)
-
Galagan, James
(author)
-
Cuomo, Christina A
(author)
-
Kistler, H Corby
(author)
-
Rep, Martijn
(author)
Related titles
-
In:Nature: Springer Science and Business Media LLC464:7287, s. 367-731476-46870028-0836
Internet link
Find in a library
-
Nature
(Search for host publication in LIBRIS)
To the university's database
- By the author/editor
-
Ma, Li-Jun
-
van der Does, H ...
-
Borkovich, Kathe ...
-
Coleman, Jeffrey ...
-
Daboussi, Marie- ...
-
Di Pietro, Anton ...
-
show more...
-
Dufresne, Marie
-
Freitag, Michael
-
Grabherr, Manfre ...
-
Henrissat, Berna ...
-
Houterman, Petra ...
-
Kang, Seogchan
-
Shim, Won-Bo
-
Woloshuk, Charle ...
-
Xie, Xiaohui
-
Xu, Jin-Rong
-
Antoniw, John
-
Baker, Scott E
-
Bluhm, Burton H
-
Breakspear, Andr ...
-
Brown, Daren W
-
Butchko, Robert ...
-
Chapman, Sinead
-
Coulson, Richard
-
Coutinho, Pedro ...
-
Danchin, Etienne ...
-
Diener, Andrew
-
Gale, Liane R
-
Gardiner, Donald ...
-
Goff, Stephen
-
Hammond-Kosack, ...
-
Hilburn, Karen
-
Hua-Van, Aurélie
-
Jonkers, Wilfrie ...
-
Kazan, Kemal
-
Kodira, Chinnapp ...
-
Koehrsen, Michae ...
-
Kumar, Lokesh
-
Lee, Yong-Hwan
-
Li, Liande
-
Manners, John M
-
Miranda-Saavedra ...
-
Mukherjee, Mala
-
Park, Gyungsoon
-
Park, Jongsun
-
Park, Sook-Young
-
Proctor, Robert ...
-
Regev, Aviv
-
Ruiz-Roldan, M C ...
-
Sain, Divya
-
Sakthikumar, Sha ...
-
Sykes, Sean
-
Schwartz, David ...
-
Turgeon, B Gilli ...
-
Wapinski, Ilan
-
Yoder, Olen
-
Young, Sarah
-
Zeng, Qiandong
-
Zhou, Shiguo
-
Galagan, James
-
Cuomo, Christina ...
-
Kistler, H Corby
-
Rep, Martijn
-
show less...
- Articles in the publication
-
Nature
- By the university
-
Uppsala University