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ZBED6 :
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Andersson, LeifSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Institutionen för husdjursgenetik (HGEN),Department of Animal Breeding and Genetics,Uppsala University
(author)
ZBED6 : the birth of a new transcription factor in the common ancestor of placental mammals
- Article/chapterEnglish2010
Publisher, publication year, extent ...
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2014-10-18
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Informa UK Limited,2010
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-160018
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-160018URI
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https://doi.org/10.4161/trns.1.3.13343DOI
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https://res.slu.se/id/publ/31831URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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A DNA transposon integrated into -the genome of a primitive mammal some 200 million years ago and, millions of years later, it evolved an essential function in the common ancestor of all placental mammals. This protein, now named ZBED6, was recently discovered because a mutation disrupting one of its binding sites, in an intron of the IGF2 gene, makes pigs grow more muscle. These findings have revealed a new mechanism for regulating muscle growth as well as a novel transcription factor that appears to be of major importance for transcriptional regulation in placental mammals.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Andersson, GöranSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Institutionen för husdjursgenetik (HGEN),Department of Animal Breeding and Genetics(Swepub:slu)50422
(author)
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Hjälm, GöranUppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi(Swepub:uu)gohja517
(author)
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Jiang, LinUppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi(Swepub:uu)linji179
(author)
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Lindblad-Toh, KerstinUppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi(Swepub:uu)kerli865
(author)
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Lindroth, AndersSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för husdjursgenetik (HGEN),Department of Animal Breeding and Genetics(Swepub:slu)51647
(author)
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Markljung, Ellen
(author)
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Nyström, Anna-Maja
(author)
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Rubin, Carl-JohanUppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi(Swepub:uu)carub021
(author)
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Sundström, ElisabethSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för husdjursgenetik (HGEN),Department of Animal Breeding and Genetics(Swepub:slu)52250
(author)
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Molin, Anna-MajaSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för husdjursgenetik (HGEN),Department of Animal Breeding and Genetics(Swepub:slu)50053
(author)
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Uppsala universitetInstitutionen för medicinsk biokemi och mikrobiologi
(creator_code:org_t)
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Sveriges lantbruksuniversitet
Related titles
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In:Transcription: Informa UK Limited1:3, s. 144-1482154-12722154-1264
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- By the author/editor
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Andersson, Leif
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Andersson, Göran
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Hjälm, Göran
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Jiang, Lin
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Lindblad-Toh, Ke ...
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Lindroth, Anders
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Markljung, Ellen
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Nyström, Anna-Ma ...
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Rubin, Carl-Joha ...
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Sundström, Elisa ...
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Molin, Anna-Maja
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- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Evolutionary Bio ...
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Transcription
- By the university
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Uppsala University
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Swedish University of Agricultural Sciences