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[11C]-PIB imaging i...
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Johansson, AndersUppsala universitet,Neurologi
(author)
[11C]-PIB imaging in patients with Parkinson's disease : preliminary results
- Article/chapterEnglish2008
Publisher, publication year, extent ...
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Elsevier BV,2008
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-16636
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-16636URI
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https://doi.org/10.1016/j.parkreldis.2007.07.010DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:117345194URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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[11C]-PIB positron emission tomography ([11C]-PIB PET) is a sensitive marker of amyloid in Alzheimer's disease (AD), but its specificity has not been fully evaluated. Vascular amyloid-β deposition is common in Parkinson's disease (PD) and α-synuclein, the major component of the Lewy bodies in PD, forms amyloid fibrils. We investigated five apparently cognitively normal PD patients with [11C]-PIB PET. The results were compared to 16 patients with AD and six healthy controls from a previous study. [11C]-PIB retention was not significantly increased in our patients who all had early stage PD. Further studies of more advanced PD patients are warranted.
Subject headings and genre
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Parkinson's disease
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PET
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PIB
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Amyloid
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Lewy bodies
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α-Synuclein
Added entries (persons, corporate bodies, meetings, titles ...)
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Savitcheva, IrinaUppsala universitet,Institutionen för medicinska vetenskaper
(author)
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Forsberg, AndersKarolinska Institutet(Swepub:uu)andfo758
(author)
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Engler, HenryUppsala universitet,Institutionen för medicinska vetenskaper(Swepub:uu)henrengl
(author)
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Långström, Bengt
(author)
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Nordberg, Agneta
(author)
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Askmark, HåkanUppsala universitet,Neurologi(Swepub:uu)hakaaskm
(author)
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Uppsala universitetNeurologi
(creator_code:org_t)
Related titles
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In:Parkinsonism & Related Disorders: Elsevier BV14:4, s. 345-3471353-80201873-5126
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