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  • Espregueira Themudo, Raquel,1978-Uppsala universitet,Enheten för radiologi (author)

Clinically unrecognized myocardial scars detected by MR are not associated with coronary artery disease

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  • LIBRIS-ID:oai:DiVA.org:uu-172070
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-172070URI

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  • Language:English
  • Summary in:English

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  • Subject category:vet swepub-contenttype
  • Subject category:ovr swepub-publicationtype

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  • Background: We have previously discovered an unexpected high prevalence of unrecognized myocardial infarction (UMI) scars by delayed-enhanced magnetic resonance imaging (DE-MRI) in the general elderly population. We now investigated if those UMIs were associated with coronary artery disease (CAD).   Methods: Eighty-eight subjects from the PIVUS study (age 75-years) who had been investigated with DE-MRI (45 with UMI and 43 without DE-MRI-detected scars) underwent coronary computed tomography angiography (CTA) to assess Agatston calcium score and coronary artery stenosis. Of those, 65 also performed an exercise ECG test.   Results: No differences were found between the subjects with UMI and the group without DE-MRI-detected scars regarding the number of coronary artery segments with significant stenosis, Agatston calcium score, or degree of ST-depression at the exercise test.   Conclusion: DE-MRI-detected UMI scars do not have an increased prevalence of coronary artery stenosis or signs of myocardial ischemia at exercise test when compared to a control group. These findings indicate that UMI scars in general are not related to CAD.  

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  • Duvernoy, OlovUppsala universitet,Enheten för radiologi (author)
  • Barbier, CharlotteUppsala universitet,Enheten för radiologi (author)
  • Johansson, LarsUppsala universitet,Enheten för radiologi (author)
  • Lind, LarsUppsala universitet,Medicin (author)
  • Ahlström, HåkanUppsala universitet,Enheten för radiologi (author)
  • Bjerner, TomasUppsala universitet,Enheten för radiologi (author)
  • Uppsala universitetEnheten för radiologi (creator_code:org_t)

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