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The demonstration i...
The demonstration in rat liver cell sap of protein kinase and phosphoprotein phosphatase active on fructose-bisphosphatase
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- Dahlqvist-Edberg, Ulla (author)
- Uppsala universitet,Institutionen för medicinsk och fysiologisk kemi,engström lorentz
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- Wretborn, Mats (author)
- Uppsala universitet,Institutionen för medicinsk och fysiologisk kemi,engström lorentz
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- Ek, Pia (author)
- Uppsala universitet,Institutionen för medicinsk och fysiologisk kemi,engström lorentz
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(creator_code:org_t)
- Elsevier BV, 1982
- 1982
- English.
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In: Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology. - : Elsevier BV. - 0167-4838 .- 1879-2588. ; 706:2, s. 239-244
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- A protein kinase active on fructose-bisphosphatase (D-fructose-1,6-bisphosphate 1-phosphohydrolase, EC 3.1.3.11) was demonstrated in rat liver cell sap. The protein kinase activity was stimulated by cyclic AMP and coincided with the activity of cyclic AMP-dependent protein kinase type I. In addition, three different peaks of phosphoprotein phosphatase active on [32P] phosphofructose-bisphosphatase were found on chromatography of rat liver cell sap on a DEAE-cellulose column. These phosphatases needed divalent cations for full activity. 5'-AMP, a negative modulator of fructose-bisphosphatase, had no effect on the phosphorylation-de-phosphorylation reactions of the enzyme. ATP and Ca2+ did not influence the dephosphorylation reaction of fructose-bisphosphatase.
Subject headings
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
Keyword
- fructose-bisphosphatase
- protein kinase
- phosphoprotein phosphatase
Publication and Content Type
- ref (subject category)
- art (subject category)
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