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Effects of similar ...
Effects of similar intakes of marine n-3 fatty acids from enriched food products and fish oil on cardiovascular risk markers in healthy human subjects
- Article/chapterEnglish2012
Publisher, publication year, extent ...
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-176244
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-176244URI
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https://doi.org/10.1017/S0007114511004508DOI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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There is convincing evidence that consumption of fish and fish oil rich in long-chain (LC) n-3 PUFA (n-3 LCPUFA), EPA (20 : 5n-3) and DHA (22 : 6n-3) reduce the risk of CHD. The aim of the present study was to investigate whether n-3 LCPUFA-enriched food products provide similar beneficial effects as fish oil with regard to incorporation into plasma lipids and effects on cardiovascular risk markers. A parallel 7-week intervention trial was performed where 159 healthy men and women were randomised to consume either 34 g fish pate (n 44), 500 ml fruit juice (n 38) or three capsules of concentrated fish oil (n 40), all contributing to a daily intake of approximately 1 g EPA and DHA. A fourth group did not receive any supplementation or food product and served as controls (n 37). Plasma fatty acid composition, serum lipids, and markers of inflammation and oxidative stress were measured. Compared with the control group, plasma n-3 LCPUFA and EPA: arachidonic acid ratio increased equally in all intervention groups. However, no significant changes in blood lipids and markers of inflammation and oxidative stress were observed. In conclusion, enriched fish pate and fruit juice represent suitable delivery systems for n-3 LCPUFA. However, although the dose given is known to reduce the risk of CVD, no significant changes were observed on cardiovascular risk markers in this healthy population.
Subject headings and genre
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Foods
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Fish oil
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n-3 Fatty acids
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Intervention
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Serum lipids
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Inflammation
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Oxidative stress
Added entries (persons, corporate bodies, meetings, titles ...)
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Lamglait, Amandine
(author)
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Eilertsen, Karl-Erik
(author)
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Falch, Eva
(author)
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Haider, Trond
(author)
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Vik, Hogne
(author)
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Hoem, Nils
(author)
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Hagve, Tor-Arne
(author)
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Basu, SamarUppsala universitet,Oxidativ stress och inflammation(Swepub:uu)samabasu
(author)
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Olsen, Elisabeth
(author)
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Seljeflot, Ingebjorg
(author)
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Nyberg, Lena
(author)
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Elind, Elisabeth
(author)
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Ulven, Stine M.
(author)
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Uppsala universitetOxidativ stress och inflammation
(creator_code:org_t)
Related titles
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In:British Journal of Nutrition107:9, s. 1339-13490007-11451475-2662
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Kirkhus, Bente
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Lamglait, Amandi ...
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Eilertsen, Karl- ...
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Falch, Eva
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Haider, Trond
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Vik, Hogne
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Hoem, Nils
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Hagve, Tor-Arne
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Basu, Samar
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Olsen, Elisabeth
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Seljeflot, Ingeb ...
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Nyberg, Lena
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Elind, Elisabeth
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Ulven, Stine M.
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Uppsala University