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Improved cognitive functions after treatment with an oral appliance in obstructive sleep apnea
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- Tegelberg, Åke (author)
- Malmö högskola,Uppsala universitet,Centrum för klinisk forskning, Västerås,Odontologiska fakulteten (OD)
- Wilhelmsson, B. (author)
- Erixon-Lindroth, N. (author)
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- Dove Press, 2012
- 2012
- English.
- In: Nature and Science of Sleep. - : Dove Press. - 1179-1608. ; 4, s. 89-96
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Objective: The objective of this study was to evaluate the effect of oral appliance (OA) treatment on cognitive functions in patients with obstructive sleep apnea (OSA). Materials and methods: In a prospective study, 50 male patients with verified moderate-to-severe OSA received an OA with mandibular advancement. The cognitive functions assessed included working memory, vigilance, executive functioning, and mental pace, measured before as well as after 6 months of treatment. Somnography was used to measure physiological treatment effects. Forty-three patients completed the 6-month follow-up study. Results: All domains of cognitive functioning measured improved after 6 months of treatment with an OA (P < 0.001). The apnea/hypopnea- and oxygen desaturation-indices decreased significantly after treatment (P < 0.01). An obvious treatment response was reached in 60% of the patients, and 54% of the patients had recovered ie, had normalized breathing during sleep. Conclusion: OA with mandibular advancement is a treatment modality for the physiological symptoms of OSA, and may have a positive impact on cognitive functions, after only 6 months of treatment.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Keyword
- Clinical trial
- Cognition
- Oral appliance
- Sleep apnea
- Treatment
Publication and Content Type
- ref (subject category)
- art (subject category)
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