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Analyses of pig gen...
Analyses of pig genomes provide insight into porcine demography and evolution
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Groenen, M. A. (author)
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Archibald, A. L. (author)
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Uenishi, H. (author)
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show more...
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Tuggle, C. K. (author)
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Takeuchi, Y. (author)
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Rothschild, M. F. (author)
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Rogel-Gaillard, C. (author)
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Park, C. (author)
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Milan, D. (author)
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Megens, H. J. (author)
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Li, S. (author)
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Larkin, D. M. (author)
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Kim, H. (author)
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Frantz, L. A. (author)
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Caccamo, M. (author)
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Ahn, H. (author)
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Aken, B. L. (author)
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Anselmo, A. (author)
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Anthon, C. (author)
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Auvil, L. (author)
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Badaoui, B. (author)
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Beattie, C. W. (author)
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Bendixen, C. (author)
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Berman, D. (author)
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Blecha, F. (author)
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- Blomberg, Jonas (author)
- Uppsala universitet,Klinisk virologi
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Bolund, L. (author)
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Bosse, M. (author)
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Botti, S. (author)
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Bujie, Z. (author)
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Byström, M. (author)
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Capitanu, B. (author)
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Carvalho-Silva, D. (author)
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Chardon, P. (author)
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Chen, C. (author)
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Cheng, R. (author)
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Choi, S. H. (author)
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Chow, W. (author)
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Clark, R. C. (author)
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Clee, C. (author)
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Crooijmans, R. P. (author)
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Dawson, H. D. (author)
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Dehais, P. (author)
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De Sapio, F. (author)
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Dibbits, B. (author)
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Drou, N. (author)
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Du, Z. Q. (author)
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Eversole, K. (author)
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Fadista, J. (author)
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Fairley, S. (author)
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Faraut, T. (author)
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Faulkner, G. J. (author)
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Fowler, K. E. (author)
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Fredholm, M. (author)
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Fritz, E. (author)
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Gilbert, J. G. (author)
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Giuffra, E. (author)
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Gorodkin, J. (author)
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Griffin, D. K. (author)
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Harrow, J. L. (author)
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- Hayward, Alexander (author)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Science for Life Laboratory, SciLifeLab
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Howe, K. (author)
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Hu, Z. L. (author)
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Humphray, S. J. (author)
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Hunt, T. (author)
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Hornshoj, H. (author)
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Jeon, J. T. (author)
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- Jern, Patric (author)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Science for Life Laboratory, SciLifeLab
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Jones, M. (author)
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Jurka, J. (author)
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Kanamori, H. (author)
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Kapetanovic, R. (author)
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Kim, J. (author)
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Kim, J. H. (author)
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Kim, K. W. (author)
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Kim, T. H. (author)
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Larson, G. (author)
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Lee, K. (author)
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Lee, K. T. (author)
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Leggett, R. (author)
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Lewin, H. A. (author)
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Li, Y. (author)
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Liu, W. (author)
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Loveland, J. E. (author)
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Lu, Y. (author)
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Lunney, J. K. (author)
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Ma, J. (author)
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Madsen, O. (author)
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Mann, K. (author)
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Matthews, L. (author)
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McLaren, S. (author)
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Morozumi, T. (author)
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Murtaugh, M. P. (author)
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Narayan, J. (author)
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Nguyen, D. T. (author)
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Ni, P. (author)
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Oh, S. J. (author)
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Onteru, S. (author)
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Panitz, F. (author)
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Park, E. W. (author)
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Park, H. S. (author)
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Pascal, G. (author)
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Paudel, Y. (author)
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Perez-Enciso, M. (author)
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Ramirez-Gonzalez, R. (author)
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Reecy, J. M. (author)
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Rodriguez-Zas, S. (author)
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Rohrer, G. A. (author)
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Rund, L. (author)
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Sang, Y. (author)
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Schachtschneider, K. (author)
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Schraiber, J. G. (author)
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Schwartz, J. (author)
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Scobie, L. (author)
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Scott, C. (author)
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Searle, S. (author)
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Servin, B. (author)
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Southey, B. R. (author)
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- Sperber, Göran (author)
- Uppsala universitet,Fysiologi
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Stadler, P. (author)
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Sweedler, J. V. (author)
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Tafer, H. (author)
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Thomsen, B. (author)
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Wali, R. (author)
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Wang, J. (author)
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White, S. (author)
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Xu, X. (author)
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Yerle, M. (author)
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Zhang, G. (author)
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Zhang, J. (author)
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Zhao, S. (author)
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Rogers, J. (author)
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Churcher, C. (author)
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Schook, L. B. (author)
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(creator_code:org_t)
- 2012-11-14
- 2012
- English.
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In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 491:7424, s. 393-398
- Related links:
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http://www.ncbi.nlm....
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show more...
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https://www.nature.c...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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show less...
Abstract
Subject headings
Close
- For 10,000 years pigs and humans have shared a close and complex relationship. From domestication to modern breeding practices, humans have shaped the genomes of domestic pigs. Here we present the assembly and analysis of the genome sequence of a female domestic Duroc pig (Sus scrofa) and a comparison with the genomes of wild and domestic pigs from Europe and Asia. Wild pigs emerged in South East Asia and subsequently spread across Eurasia. Our results reveal a deep phylogenetic split between European and Asian wild boars approximately 1 million years ago, and a selective sweep analysis indicates selection on genes involved in RNA processing and regulation. Genes associated with immune response and olfaction exhibit fast evolution. Pigs have the largest repertoire of functional olfactory receptor genes, reflecting the importance of smell in this scavenging animal. The pig genome sequence provides an important resource for further improvements of this important livestock species, and our identification of many putative disease-causing variants extends the potential of the pig as a biomedical model.
Subject headings
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
- NATURVETENSKAP -- Biologi -- Evolutionsbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Evolutionary Biology (hsv//eng)
- LANTBRUKSVETENSKAPER -- Husdjursvetenskap (hsv//swe)
- AGRICULTURAL SCIENCES -- Animal and Dairy Sience (hsv//eng)
Keyword
- Biology with specialization in Evolutionary Genetics
- Biologi med inriktning mot evolutionär genetik
- Biologi med inriktning mot evolutionär funktionsgenomik
- Biology with specialization in Evolutionary Functional Genomics
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
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Nature
(Search for host publication in LIBRIS)
To the university's database
- By the author/editor
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Groenen, M. A.
-
Archibald, A. L.
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Uenishi, H.
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Tuggle, C. K.
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Takeuchi, Y.
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Rothschild, M. F ...
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show more...
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Rogel-Gaillard, ...
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Park, C.
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Milan, D.
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Megens, H. J.
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Li, S.
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Larkin, D. M.
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Kim, H.
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Frantz, L. A.
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Caccamo, M.
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Ahn, H.
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Aken, B. L.
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Anselmo, A.
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Anthon, C.
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Auvil, L.
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Badaoui, B.
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Beattie, C. W.
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Bendixen, C.
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Berman, D.
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Blecha, F.
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Blomberg, Jonas
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Bolund, L.
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Bosse, M.
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Botti, S.
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Bujie, Z.
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Byström, M.
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Capitanu, B.
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Carvalho-Silva, ...
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Chardon, P.
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Chen, C.
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Cheng, R.
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Choi, S. H.
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Chow, W.
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Clark, R. C.
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Clee, C.
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Crooijmans, R. P ...
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Dawson, H. D.
-
Dehais, P.
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De Sapio, F.
-
Dibbits, B.
-
Drou, N.
-
Du, Z. Q.
-
Eversole, K.
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Fadista, J.
-
Fairley, S.
-
Faraut, T.
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Faulkner, G. J.
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Fowler, K. E.
-
Fredholm, M.
-
Fritz, E.
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Gilbert, J. G.
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Giuffra, E.
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Gorodkin, J.
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Griffin, D. K.
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Harrow, J. L.
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Hayward, Alexand ...
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Howe, K.
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Hu, Z. L.
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Humphray, S. J.
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Hunt, T.
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Hornshoj, H.
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Jeon, J. T.
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Jern, Patric
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Jones, M.
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Jurka, J.
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Kanamori, H.
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Kapetanovic, R.
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Kim, J.
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Kim, J. H.
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Kim, K. W.
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Kim, T. H.
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Larson, G.
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Lee, K.
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Lee, K. T.
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Leggett, R.
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Lewin, H. A.
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Li, Y.
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Liu, W.
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Loveland, J. E.
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Lu, Y.
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Lunney, J. K.
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Ma, J.
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Madsen, O.
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Mann, K.
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Matthews, L.
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McLaren, S.
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Morozumi, T.
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Murtaugh, M. P.
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Narayan, J.
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Nguyen, D. T.
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Ni, P.
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Oh, S. J.
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Onteru, S.
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Panitz, F.
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Park, E. W.
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Park, H. S.
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Pascal, G.
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Paudel, Y.
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Perez-Enciso, M.
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Ramirez-Gonzalez ...
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Reecy, J. M.
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Rodriguez-Zas, S ...
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Rohrer, G. A.
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Rund, L.
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Sang, Y.
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Schachtschneider ...
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Schraiber, J. G.
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Schwartz, J.
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Scobie, L.
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Scott, C.
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Searle, S.
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Servin, B.
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Southey, B. R.
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Sperber, Göran
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Stadler, P.
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Sweedler, J. V.
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Tafer, H.
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Thomsen, B.
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Wali, R.
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Wang, J.
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White, S.
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Xu, X.
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Yerle, M.
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Zhang, G.
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Zhang, J.
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Zhao, S.
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Rogers, J.
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Churcher, C.
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Schook, L. B.
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show less...
- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Genetics
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Evolutionary Bio ...
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- AGRICULTURAL SCIENCES
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AGRICULTURAL SCI ...
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and Animal and Dairy ...
- Articles in the publication
-
Nature
- By the university
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Uppsala University