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Fear conditioning a...
Fear conditioning and brain activity : a positron emission tomography study in humans.
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Fischer, H (author)
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- Andersson, J L (author)
- Uppsala universitet,Institutionen för psykologi
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- Furmark, T (author)
- Uppsala universitet,Pedagogiska institutionen
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- Fredrikson, M (author)
- Uppsala universitet,Institutionen för psykologi
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(creator_code:org_t)
- 2000
- 2000
- English.
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In: Behav Neurosci. - 0735-7044. ; 114:4, s. 671-80
- Related links:
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http://www.ncbi.nlm....
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https://urn.kb.se/re...
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Abstract
Subject headings
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- Regional cerebral blood flow (rCBF) was measured with H2 (15)O positron emission tomography in 8 healthy women before and after fear conditioning (i.e., paired shocks) and unpaired shocks to videotape cues. Conditioning was supported by enhanced peripheral nervous system recordings and subjective ratings. Fear conditioning increased rCBF in the central gray of the midbrain; bilaterally in the hypothalamus, the thalamus, and the left striatum; and in the right and left anterior cingulate and right prefrontal cortices. Regional CBF was attenuated bilaterally in the right and left prefrontal, temporal (including the amygdala), parietal, and occipital cortices, and in the left orbitofrontal cortex. When compared with unpaired shock presentations, fear conditioning resulted in elevated rCBF in the left cerebellum. Hence, in the present paradigm, only neural activity in the left cerebellum solely reflected processes associated with true Pavlovian conditioning.
Keyword
- Adult
- Arousal/physiology
- Brain/blood supply/*radionuclide imaging
- Brain Mapping
- Cerebellum/physiology/radionuclide imaging
- Conditioning; Classical/*physiology
- Dominance; Cerebral/physiology
- Fear/*physiology
- Female
- Humans
- Regional Blood Flow/physiology
- Research Support; Non-U.S. Gov't
- Tomography; Emission-Computed
Publication and Content Type
- vet (subject category)
- art (subject category)
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