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CYSTEINE PROTEASE I...
CYSTEINE PROTEASE INHIBITORS
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Ayesa, S. (author)
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Belfrage, Anna Karin (author)
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Classon, B. (author)
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Grabowska, U. (author)
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Hewitt, E. (author)
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Ivanov, V. (author)
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Jönsson, D. (author)
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Kahnberg, P. (author)
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Lind, P. (author)
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Nilsson, M. (author)
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Odén, L. (author)
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Pelcman, M. (author)
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Wähling, H. (author)
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- 2011
- English.
- Related links:
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https://urn.kb.se/re...
Abstract
Subject headings
Close
- Compounds of the formula IwhereinR1a is H; and R1b is C1-C6 alkyl, Carbocyclyl or Het; orR1a and R1b together define a saturated cyclic amine with 3-6 ring atoms;R2a and R2b are H, halo, C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy; orR2a and R2b together with the carbon atom to which they are attached form a C3-C6cycloalkyl;R3 is a branched C5-C10alkyl chain, C2-C4haloalkyl or C3-C7cycloalkylmethyl,R4 is Het, Carbocyclyl,optionally substituted as defined in the specification and pharmaceutically acceptable salts,hydrates and N-oxides thereof; are inhibitors of cathepsin S and have utility in the treatment of psoriasis, autoimmune disorders and other disorders such as asthma, arteriosclerosis, COPD and chronic pain.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Läkemedelskemi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Medicinal Chemistry (hsv//eng)
Keyword
- Medicinal Chemistry
- Läkemedelskemi
Publication and Content Type
- pop (subject category)
- pat (subject category)
To the university's database
- By the author/editor
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Ayesa, S.
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Belfrage, Anna K ...
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Classon, B.
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Grabowska, U.
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Hewitt, E.
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Ivanov, V.
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show more...
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Jönsson, D.
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Kahnberg, P.
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Lind, P.
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Nilsson, M.
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Odén, L.
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Pelcman, M.
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Wähling, H.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Medicinal Chemis ...
- By the university
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Uppsala University