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Comparison of ultra...
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Amini, HashemUppsala universitet,Obstetrik & gynekologi,Obstetrisk forskning/Axelsson
(author)
Comparison of ultrasound and autopsy findings in pregnancies terminated due to fetal anomalies
- Article/chapterEnglish2006
Publisher, publication year, extent ...
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Wiley,2006
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-21374
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-21374URI
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https://doi.org/10.1080/00016340600880886DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:1958695URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Objective. To compare antenatal diagnoses with autopsy findings in pregnancies terminated after ultrasound detection of fetal anomalies. A second aim was to study the quality of antenatal fetal diagnosis over time. Design. Retrospective, multicenter study over two consecutive six-year periods in Uppsala and Stockholm. Setting. Cases were identified through fetal autopsy reports. Subjects. Three hundred and twenty-eight fetuses from pregnancies terminated between 1992 and 2003 because of ultrasonographically diagnosed anomalies. Main outcome measures. The findings at the last ultrasound examination were compared with the autopsy reports. Results. In 299 cases (91.2%) ultrasound findings either exactly matched or were essentially similar to the autopsy findings. In 23 cases (7%) ultrasound findings were not confirmed at autopsy, but the postnatal findings were at least as severe as the antenatal ones. In six cases (1.8%) termination was performed for an anomaly which proved to be less severe than was predicted by ultrasound. The number of such cases was the same in both six-year periods, while the total number of cases increased from 113 in the first to 215 in the second period. Fetal examination provided further diagnostic information in 47% of the cases. In 10% a syndrome was disclosed. Conclusion. Termination of pregnancy was not always based on a correct antenatal diagnosis. All fetuses but one from terminated pregnancies had evident anomalies. In six cases (1.8%) the decision to terminate was based on suboptimal prognostic and diagnostic information. Fetal autopsy by an experienced perinatal pathologist is essential to provide a definitive diagnosis.
Subject headings and genre
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fetal anomaly
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ultrasound
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antenatal diagnosis
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pregnancy termination
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fetal autopsy
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MEDICINE
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MEDICIN
Added entries (persons, corporate bodies, meetings, titles ...)
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Antonsson, Per
(author)
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Papadogiannakis, NikosKarolinska Institutet
(author)
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Ericson, KatharinaUppsala universitet,Institutionen för genetik och patologi
(author)
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Pilo, Christina
(author)
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Eriksson, LarsUppsala universitet,Institutionen för genetik och patologi
(author)
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Westgren, MagnusKarolinska Institutet
(author)
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Axelsson, OveUppsala universitet,Obstetrik & gynekologi,Obstetrisk forskning/Axelsson(Swepub:uu)oveaxels
(author)
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Uppsala universitetObstetrik & gynekologi
(creator_code:org_t)
Related titles
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In:Acta Obstetricia et Gynecologica Scandinavica: Wiley85:10, s. 1208-12160001-63491600-0412
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