Long-term variation in influenza A virus prevalence and subtype diversity in migratory mallards in northern Europe.

Latorre-Margalef, Neus (author): Linnéuniversitetet,Institutionen för biologi och miljö (BOM),Univ Georgia, USA,Ctr Ecol & Evolut Microbial Model Syst EEMiS

Tolf, Conny (author): Linnéuniversitetet,Institutionen för biologi och miljö (BOM),Ctr Ecol & Evolut Microbial Model Syst EEMiS

Avril, Alexis (author): Linnéuniversitetet,Institutionen för biologi och miljö (BOM),Erasmus MC, Netherlands

Bengtsson, Daniel (author): Linnéuniversitetet,Institutionen för biologi och miljö (BOM)

Wille, Michelle (author): Linnéuniversitetet,Institutionen för biologi och miljö (BOM)

Fouchier, Ron A M (author)

Olsen, Björn (author): Uppsala universitet,Infektionssjukdomar,Uppsala University, Sweden

Waldenström, Jonas, 1975- (author): Linnéuniversitetet,Institutionen för biologi och miljö (BOM),Ctr Ecol & Evolut Microbial Model Syst EEMiS;Zoonotic Ecology and Epidemiology

(creator_code:org_t)

2014-04-22
2014
English.
In: Proceedings of the Royal Society of London. Biological Sciences. - : The Royal Society. - 0962-8452 .- 1471-2954. ; 281:1781, s. 20140098-

Related links:: https://royalsociety...; show more...; https://urn.kb.se/re...; https://doi.org/10.1...; https://urn.kb.se/re...; show less...

Abstract Subject headings

Data on long-term circulation of pathogens in wildlife populations are seldom collected, and hence understanding of spatial-temporal variation in prevalence and genotypes is limited. Here, we analysed a long-term surveillance series on influenza A virus (IAV) in mallards collected at an important migratory stopover site from 2002 to 2010, and characterized seasonal dynamics in virus prevalence and subtype diversity. Prevalence dynamics were influenced by year, but retained a common pattern for all years whereby prevalence was low in spring and summer, but increased in early autumn with a first peak in August, and a second more pronounced peak during October-November. A total of 74 haemagglutinin (HA)/neuraminidase (NA) combinations were isolated, including all NA and most HA (H1-H12) subtypes. The most common subtype combinations were H4N6, H1N1, H2N3, H5N2, H6N2 and H11N9, and showed a clear linkage between specific HA and NA subtypes. Furthermore, there was a temporal structuring of subtypes within seasons based on HA phylogenetic relatedness. Dissimilar HA subtypes tended to have different temporal occurrence within seasons, where the subtypes that dominated in early autumn were rare in late autumn, and vice versa. This suggests that build-up of herd immunity affected IAV dynamics in this system.

By the author/editor: Latorre-Margalef ...; Tolf, Conny; Grosbois, Vladim ...; Avril, Alexis; Bengtsson, Danie ...; Wille, Michelle; show more...; Osterhaus, Alber ...; Fouchier, Ron A ...; Olsen, Björn; Waldenström, Jon ...; show less...

About the subject

NATURAL SCIENCES: NATURAL SCIENCES; and Biological Scien ...; and Microbiology

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.