Search: onr:"swepub:oai:DiVA.org:uu-230926" >
Long-term memory pe...
Long-term memory performance after surgical treatment of unilateral temporal lobe epilepsy (TLE)
-
Jutila, Leena (author)
-
Aikia, Marja (author)
-
Immonen, Arto (author)
-
show more...
-
Mervaala, Esa (author)
-
- Alafuzoff, Irina (author)
- Uppsala universitet,Molekylär och morfologisk patologi
-
Kalviainen, Reetta (author)
-
show less...
-
(creator_code:org_t)
- Elsevier BV, 2014
- 2014
- English.
-
In: Epilepsy Research. - : Elsevier BV. - 0920-1211 .- 1872-6844. ; 108:7, s. 1228-1237
- Related links:
-
https://urn.kb.se/re...
-
show more...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Long-term cognitive and memory performance after surgical treatment of unilateral temporal lobe epilepsy (TLE) was investigated in a series of 98 patients. Neuropsychological evaluation was performed preoperatively and after one and three years postoperatively. Fifty-eight patients (59%) became seizure-free (Engel's class I). Verbal learning and memory declined in long-term follow-up in both left and right TLE groups. Visual memory remained stable. Ongoing postoperative seizures were related to decline in the immediate recall of logical prose, and postoperative seizure-freedom to improvement in verbal fluency in patients with left TLE. There was significant variability in the individual postoperative long-term memory performance. Left side of surgery, better baseline performance and older age at surgery were identified as risk factors for individual decline in delayed verbal memory. Selected patients undergoing surgery for drug-resistant TLE are at risk for significant postoperative memory decline especially after left temporal lobe surgery. Preoperative counseling and long-term follow-up of cognitive performance in individual patients is recommended. Additionally, more accurate predictors of individual postoperative memory performance would be needed.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Keyword
- Epilepsy surgery
- Temporal lobe epilepsy
- Outcome
- Memory
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database