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  • Koltowski, Lukasz1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland (author)

Quality of Life in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention-Radial Versus Femoral Access (from the OCEAN RACE Trial)

  • Article/chapterEnglish2014

Publisher, publication year, extent ...

  • Elsevier BV,2014
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:uu-231996
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-231996URI
  • https://doi.org/10.1016/j.amjcard.2014.05.030DOI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Numerous studies have compared transradial (TR) versus transfemoral (TF) access for percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial infarction. These studies have focused on clinical efficacy and safety; yet little is known about the effect of the vessel access on the health-related quality of life (HRQoL). In the present study, patients were randomly assigned to TR (n = 52) or TF (n = 51) access groups. Generic (EQ-5D-3L) and cardiac-specific (Quality of Life Index and MacNew) tools were used to assess HRQoL before PCI and 2 hours and 4 days after PCI. Baseline HRQoL was comparable in both groups and improved after PCI. The mean +/- SD EQ-5D-3L health utility score 2 hours after PCI was 0.46 +/- 0.291 and was higher in the TR group (TR: 0.60 +/- 0.299 versus TF: 0.32 +/- 0.283, p <0.001). Patients in the TR group reported fewer problems with mobility (TR: 71.7% vs TF: 94.4%, p <0.01) and self-care (TR: 62.5% vs TF: 97.2%, p <0.001). At day 4, fewer patients reported problems with anxiety and/or depression in the TR group than in the TF group (TR: 42.9% vs TF: 75.0%, p <0.001); no differences between groups in other measures were observed (Quality of Life Index and MacNew). The N-terminal of the prohormone brain natriuretic peptide levels were inversely correlated with EQ-5D-3L visual analog scale (r = -0.348, p <0.05) and EQ-5D-3L health utility score (r = -0.322, p <0.05). There was a correlation between in-hospital mortality and 2 MacNew domains: physical (r = -0.329, p <0.05) and emotional (r = -0.374, p <0.01). In conclusion, radial access should be the preferred approach in patients with ST-segment elevation myocardial infarction undergoing PCI when considering HRQoL. Radial access is associated with fewer problems with mobility and self-care and better psychological outcome after PCI.

Subject headings and genre

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  • Koltowska-Häggström, Maria,1957-Uppsala universitet,Institutionen för kvinnors och barns hälsa,Barnendokrinologisk forskning/Gustafsson(Swepub:uu)makot956 (author)
  • Filipiak, Krzysztof Jerzy1st Department of Cardiology, Medical University of Warsaw, Poland (author)
  • Kochman, Janusz1st Department of Cardiology, Medical University of Warsaw, Poland (author)
  • Golicki, DominikDepartment of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland (author)
  • Pietrasik, Arkadiusz1st Department of Cardiology, Medical University of Warsaw, Poland (author)
  • Huczek, Zenon1st Department of Cardiology, Medical University of Warsaw, Poland (author)
  • Balsam, Pawel1st Department of Cardiology, Medical University of Warsaw, Poland (author)
  • Scibisz, Anna1st Department of Cardiology, Medical University of Warsaw, Poland (author)
  • Opolski, Grzegorz1st Department of Cardiology, Medical University of Warsaw, Poland (author)
  • 1st Department of Cardiology, Medical University of Warsaw, Warsaw, PolandInstitutionen för kvinnors och barns hälsa (creator_code:org_t)

Related titles

  • In:American Journal of Cardiology: Elsevier BV114:4, s. 516-5210002-91491879-1913

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