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Hydroxyapatite coat...
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Hailer, Nils PUppsala universitet,Ortopedi
(author)
Hydroxyapatite coating does not improve uncemented stem survival after total hip arthroplasty! : An analysis of 116,069 THAs in the Nordic Arthroplasty Register Association (NARA) database
- Article/chapterEnglish2015
Publisher, publication year, extent ...
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2014-09
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Medical Journals Sweden AB,2015
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printrdacarrier
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LIBRIS-ID:oai:DiVA.org:uu-232491
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-232491URI
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https://doi.org/10.3109/17453674.2014.957088DOI
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
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Background and purposeIt is still being debated whether HA coating of uncemented stems used in total hip arthroplasty (THA) improves implant survival. We therefore investigated different uncemented stem brands, with and without HA coating, regarding early and long-term survival.Patients and methods We identified 152,410 THA procedures using uncemented stems that were performed between 1995 and 2011 and registered in the Nordic Arthroplasty Register Association (NARA) database. We excluded 19,446 procedures that used stem brands less than 500 times in each country, procedures performed due to diagnoses other than osteoarthritis or pediatric hip disease, and procedures with missing information on the type of coating. 22 stem brands remained (which were used in 116,069 procedures) for analysis of revision of any component. 79,192 procedures from Denmark, Norway, and Sweden were analyzed for the endpoint stem revision. Unadjusted survival rates were calculated according to Kaplan-Meier, and Cox proportional hazards models were fitted in order to calculate hazard ratios (HRs) for the risk of revision with 95% confidence intervals (CIs).ResultsUnadjusted 10-year survival with the endpoint revision of any component for any reason was 92.1% (CI: 91.8-92.4). Unadjusted 10-year survival with the endpoint stem revision due to aseptic loosening varied between the stem brands investigated and ranged from 96.7% (CI: 94.4-99.0) to 99.9% (CI: 99.6-100). Of the stem brands with the best survival, stems with and without HA coating were found. The presence of HA coating was not associated with statistically significant effects on the adjusted risk of stem revision due to aseptic loosening, with an HR of 0.8 (CI: 0.5-1.3; p = 0.4). The adjusted risk of revision due to infection was similar in the groups of THAs using HA-coated and non-HA-coated stems, with an HR of 0.9 (CI: 0.8-1.1; p = 0.6) for the presence of HA coating. The commonly used Bimetric stem (n = 25,329) was available both with and without HA coating, and the adjusted risk of stem revision due to aseptic loosening was similar for the 2 variants, with an HR of 0.9 (CI: 0.5-1.4; p = 0.5) for the HA-coated Bimetric stem.Interpretation Uncemented HA-coated stems had similar results to those of uncemented stems with porous coating or rough sand-blasted stems. The use of HA coating on stems available both with and without this surface treatment had no clinically relevant effect on their outcome, and we thus question whether HA coating adds any value to well-functioning stem designs.
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Lazarinis, StergiosUppsala universitet,Ortopedi(Swepub:uu)stela456
(author)
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Mäkelä, Keijo T
(author)
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Eskelinen, Antti
(author)
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Fenstad, Anne M
(author)
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Hallan, Geir
(author)
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Havelin, Leif
(author)
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Overgaard, Søren
(author)
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Pedersen, Alma B
(author)
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Mehnert, Frank
(author)
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Kärrholm, Johan
(author)
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Uppsala universitetOrtopedi
(creator_code:org_t)
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In:Acta Orthopaedica: Medical Journals Sweden AB86:1, s. 18-251745-36741745-3682
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Hailer, Nils P
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Lazarinis, Sterg ...
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Mäkelä, Keijo T
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Eskelinen, Antti
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Fenstad, Anne M
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Hallan, Geir
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show more...
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Havelin, Leif
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Overgaard, Søren
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Pedersen, Alma B
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Mehnert, Frank
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Kärrholm, Johan
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Orthopaedics
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Acta Orthopaedic ...
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Uppsala University