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High-frequency jet ...
High-frequency jet ventilation shortened the duration of gas embolization during laparoscopic liver resection in a porcine model
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- Fors, Diddi (author)
- Uppsala universitet,Anestesiologi och intensivvård
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- Eiriksson, K. (author)
- Uppsala universitet,Institutionen för kirurgiska vetenskaper
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Waage, A. (author)
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- Arvidsson, D. (author)
- Uppsala universitet,Institutionen för kirurgiska vetenskaper
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- Rubertsson, Sten (author)
- Uppsala universitet,Anestesiologi och intensivvård
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(creator_code:org_t)
- Elsevier BV, 2014
- 2014
- English.
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In: British Journal of Anaesthesia. - : Elsevier BV. - 0007-0912 .- 1471-6771. ; 113:3, s. 484-490
- Related links:
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http://bjanaesthesia...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Background. Positive pressure mechanical ventilation causes rhythmic changes in thoracic pressure and central blood flow. If entrainment occurs, it could be easier for carbon dioxide to enter through a wounded vein during laparoscopic liver lobe resection (LLR). High-frequency jet ventilation (HFJV) is a ventilating method that does not cause pronounced pressure or blood flow changes. This study aimed to investigate whether HFJV could influence the frequency, severity, or duration of gas embolism (GE) during LLR. Methods. Twenty-four anaesthetized piglets underwent lobe resection and were randomly assigned to either normal frequency ventilation (NFV) or HFJV (n=12 per group). During resection, a standardized injury to the left hepatic vein was created to increase the risk of GE. Haemodynamic and respiratory variables were monitored. Online blood gas monitoring and transoesophageal echocardiography were used. GE occurrence and severity were graded as 0 (none), 1 (minor), or 2 (major), depending on the echocardiography results. Results. GE duration was shorter in the HFJV group (P=0.008). However, no differences were found between the two groups in the frequency or severity of embolism. Incidence of Grade 2 embolism was less than that found in previous studies and physiological responses to embolism were variable. Conclusion. HFJV shortened the mean duration of GE during LLR and was a feasible ventilation method during the procedure. Individual physiological responses to GE were unpredictable.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Keyword
- animal model
- gas embolism
- high frequency jet ventilation
- laparoscopic
- liver resection
Publication and Content Type
- ref (subject category)
- art (subject category)
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