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A Case Report of Improved Metabolic Control After Conversion From Everolimus to Cyclosporin A : Role of Adipose Tissue Mechanisms?
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- Pereira, Maria J. (author)
- Uppsala universitet,Klinisk diabetologi och metabolism
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- Eriksson, Jan W. (author)
- Uppsala universitet,Klinisk diabetologi och metabolism
- Svensson, M. K. (author)
- (creator_code:org_t)
- Elsevier BV, 2014
- 2014
- English.
- In: Transplantation Proceedings. - : Elsevier BV. - 0041-1345 .- 1873-2623. ; 46:7, s. 2377-2380
- Journal article (peer-reviewed)
Abstract
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- Background. New-onset diabetes after transplantation is associated with an increase in risk of graft failure, cardiovascular disease, and mortality. Therefore, it compromises the overall beneficial outcome of organ transplantation. Case Report. A patient with new-onset diabetes after renal transplantation showed glucose and lipid metabolism improvements after switching immunosuppressant from everolimus to cyclosporin A. A subcutaneous adipose tissue biopsy displayed changes in gene and protein expression that could contribute to the clinical improvement of hyperglycemia and dyslipidemia.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Immunologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Immunology in the medical area (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
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