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Combined lowering o...
Combined lowering of low grade systemic inflammation and insulin resistance in metabolic syndrome patients treated with Ginkgo biloba
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- Siegel, Günter (author)
- Uppsala universitet,Institutionen för farmaci
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Ermilov, E. (author)
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Knes, O. (author)
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Rodriguez, M. (author)
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(creator_code:org_t)
- Elsevier BV, 2014
- 2014
- English.
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In: Atherosclerosis. - : Elsevier BV. - 0021-9150 .- 1879-1484. ; 237:2, s. 584-588
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- In a clinical pilot study with eleven metabolic syndrome patients, a simultaneous decrease in hs-CRP from 8.85 +/- 4.09 to 4.92 +/- 2.51 mg/L (-44.4%) (p < 0.0436) and HOMA-IR from 3.07 +/- 0.63 to 2.60 +/- 0.51 mU/L x mg/dL (-15.3%) (p < 0.0120) as well as a beneficial change of arteriosclerotic, inflammatory and oxidative stress biomarkers were detected after 2-month treatment with Ginkgo biloba. Furthermore, both IL-6 (-12.9%, p < 0.0407) and nanoplaque formation (-14.3%, p < 0.0077) were additionally reduced. According to a large clinical trial elucidating the importance of insulin resistance and low-grade systemic inflammation for cardiovascular disease and overall mortality risk, these data might indicate a CVD/total mortality risk reduction.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Metabolic syndrome patients
- High-sensitivity C-reactive protein (hs-CRP)
- Homeostasis model assessment of insulin resistance (HOMA-IR)
- CVD/total mortality risk
- Ginkgo biloba
Publication and Content Type
- ref (subject category)
- art (subject category)
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